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Materno-foetal transport and metabolism of TRP in rat term placenta. (A) Maternal TRP rapidly crossed the placenta and reached the foetal circulation to a high extent, but concentration-dependently. (B) Release of placental 5-HT, synthesized from maternal TRP, into the foetal circulation was evident only after inhibition of MAO-A by phenelzine (100 μM) at 40 min of perfusion. Data are median + IQR (n> 3) for each test condition
