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. 2021 Feb 25;2:647134. doi: 10.3389/falgy.2021.647134

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Copyright © 2021 Walker, Ferrie, Hoji, Schroeder-Carter, Cohen, Schnaar and Cook-Mills.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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P4rr decreased β-glucosyl ceramides in lung and liver of pups of allergic mothers. Moms were treated as in Figure 6A and pup tissues were collected on PND13. Tissue β-glucosyl ceramides were separated by column chromatography and then analyzed by mass spectrometry. (A) Pup lung. (B) Pup liver. n = 8–10 mice per group for a representative experiment of two experiments. *p < 0.05 compared to NT, OVA allergic mother, crimson red highlighted chain lengths are above the panels.