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. 2021 Jul 30;13(15):3833. doi: 10.3390/cancers13153833

Figure 6.

Figure 6

HIF-1α inhibition under hypoxia decreases HR in response to photons and C-ions. (a) Kinetics of RAD51 foci after X-rays and C-ions HIF-1α ± siHIF-1α. The percentages of foci per nucleus were reported to the reference (X-rays-Normoxia) and calculated for each condition (means ± SD). (b) Effect of the silencing of HIF-1α under hypoxia on RAD51 expression. The RAD51 percentages between hypoxia ± siHIF-1α were statistically compared (Student’s t-Tests, Holm–Sidak method, α = 0.5) (n = 3). * p < 0.05.