Figure 2.

Illustration of a meningothelial meningioma in the AdCre; Nf2flox/flox; Ink4ab−/− model. Left image shows a coronal section of the whole cranium, with a massive right convexity meningioma (star) causing mass effect on the brain (Br). The lesion is centered at the Adenovirus injection site, a few millimeters lateral from the falx (arrows). Upper right image shows the meningioma at higher magnification; note that the brain cortex is not invaded in this case. Lower right image shows the tumoral architecture at higher magnification. Note the classical aspect of cellular whorl (star) and the close relationship with the skull convexity bone (Bo).