Table 2.
Variables associated with the cortical or subcortical pattern, motor deficit and extent of resection: Fisher Exact tests or Pearson Chi-square tests were performed for all the associations, with the exception of the tumor volume variable, where a one-way ANOVA was used; only significant factors are shown. The Advanced Brain Mapping Technique analysis refers to the comparison of EOR between patients submitted to the advanced Brain Mapping technique (YES) and those (historical cohort of 51 patients) who were submitted to the standard mapping (NO, To5).
| Factors Associated with Cortical Pattern | Factors Associated with Subcortical Pattern | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Normal | % | Distorted | % | p | Normal | % | Distorted | % | p | ||||||
| Previous | No | 23 | 69.7 | 10 | 30.3 | 0.01 | Previous | No | 22 | 66.7 | 11 | 33.3 | 0.01 | ||
| treatment | Yes | 13 | 39.4 | 20 | 60.6 | treatment | Yes | 12 | 36.4 | 21 | 63.6 | ||||
| Controlled | Yes | 27 | 65.9 | 14 | 34.1 | 0.02 | Controlled pre-op seizures | Yes | 25 | 61 | 16 | 39 | 0.04 | ||
| pre-op seizures | No | 9 | 36 | 16 | 64 | No | 9 | 36 | 16 | 64 | |||||
| Subcortical pattern | normal | 34 | 100 | 0 | 0 | 0.001 | |||||||||
| distorted | 2 | 7 | 30 | 93 | |||||||||||
| FACTORS ASSOCIATED WITH MOTOR DEFICIT AT 5 DAYS | FACTORS ASSOCIATED WITH MOTOR DEFICIT AT 1 MONTH | ||||||||||||||
| DEFICIT | DEFICIT | ||||||||||||||
| Yes | % | No | % | p | Yes | % | No | % | p | ||||||
| Berger Classification |
1 | 19 | 61 | 12 | 39 | 0.01 | Resection | Partial/Subtotal | 2 | 25 | 6 | 75 | 0.03 | ||
| 2 | 23 | 92 | 2 | 8 | Total | 1 | 2 | 57 | 98 | ||||||
| 3 | 9 | 90 | 1 | 10 | |||||||||||
| Border | Irregular | 44 | 88 | 6 | 12 | 0.001 | |||||||||
| Well-defined | 7 | 44 | 9 | 56 | |||||||||||
| Histology | LGG | 34 | 94 | 2 | 6 | 0.001 | |||||||||
| HGG | 13 | 43 | 17 | 57 | |||||||||||
| FACTORS ASSOCIATED WITH MRC AT 5 DAYS | FACTORS ASSOCIATED WITH MRC AT 1 MONTH | ||||||||||||||
| MRC | % | MRC | % | MRC | % | p | MRC | % | MRC | % | p | ||||
| 3 | 4 | 5 | 4 | 5 | |||||||||||
| Duration | >6m | 13 | 26.5 | 32 | 6.3 | 4 | 8.2 | 0.04 | Resection | Partial/ Subtotal |
3 | 38 | 5 | 62 | 0 |
| <6m | 9 | 52.9 | 5 | 29.4 | 3 | 17.6 | Total | 1 | 2 | 57 | 98 | ||||
| Border | Irregular | 21 | 42 | 27 | 54 | 2 | 4 | 0.01 | Histology | LGG | 0 | 0 | 36 | 100 | 0.04 |
| Defined | 1 | 6.3 | 10 | 62.5 | 5 | 31.3 | HGG | 4 | 13 | 26 | 87 | ||||
| FACTORS ASSOCIATED WITH EOR | |||||||||||||||
| Partial/Subtotal | d.s/% | Total | d.s/% | p | Cortical pattern |
normal | 0 | 0 | 36 | 100 | 0.04 | ||||
| Volume pre-op |
mean | 24.5 | 5.6 | 4.7 | 4.3 | 0.01 | distorted | 4 | 13 | 26 | 87 | ||||
| Advanced Brain Mapping Technique | No | 14 | 27 | 37 | 73 | 0.03 | Subcortical pattern |
normal | 0 | 0 | 34 | 100 | 0.04 | ||
| Yes | 8 | 12 | 58 | 88 | distorted | 4 | 13 | 28 | 87.1 | ||||||