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. 2021 Jul 27;13(15):3770. doi: 10.3390/cancers13153770

Table 1.

OS values incl. HRs in different AED categories within the whole cohort and subgroup with adjuvant chemoradiation with TMZ (CCRT + TMZ-subgroup).

In the Whole Cohort In the CCRT + TMZ-Subgroup
Median 95% CI HR 95% CI p-Value Median 95% CI HR 95% CI p-Value
Mono AED vs. Combined AED
Mono AED 15.0 13.01–16.99 1.23 0.65–2.33 0.532 15.0 13.01–16.99 1.23 0.65–2.33 0.532
Combined AED 10.27 7.94–12.59 10.27 7.94–12.59
NEIAED vs. EIAED
NEIAED 11.8 9.96–13.64 0.89 0.61–1.28 0.520 14.5 12.45–16.55 1.17 0.71–1.92 0.532
EIAED 9.67 4.67–14.67 15.07 11.42–18.72
LEV vs. Any Other AED
LEV 12.8 10.82–14.78 0.70 0.54–0.89 0.004 15 12.32–17.68 0.78 0.59–1.05 0.100
Other AED 9.07 6.68–11.46 14.23 10.27–18.19
LEV vs. No LEV
LEV 12.8 10.82–14.78 0.68 0.57–0.81 <0.0001 15 12.32–17.68 0.73 0.60–0.89 0.002
No LEV 8.77 7.77–9.77 12.13 11.24–13.03

Abbreviations: CI—confidence interval. HR—hazard ratio.