Table 3.
PFS values incl. HRs in different AED categories within the whole cohort and subgroup with adjuvant chemoradiation with TMZ (CCRT + TMZ-subgroup).
| In the Whole Cohort | In the CCRT + TMZ-Subgroup | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Median | 95% CI | HR | 95% CI | p-Value | Median | 95% CI | HR | 95% CI | p-Value | |
| Mono AED vs. Combined AED | ||||||||||
| Mono AED | 8.0 | 6.4–9.6 | 1.33 | 0.62–2.86 | 0.464 | 8.0 | 6.4–9.6 | 1.33 | 0.62–2.86 | 0.464 |
| Combined AED | 4.0 | 1.52–6.48 | 4.0 | 1.52–6.48 | ||||||
| NEIAED vs. EIAED | ||||||||||
| NEIAED | 6.0 | 5.0–7.0 | 0.59 | 0.37–0.96 | 0.034 | 8.0 | 6.37–9.63 | 0.83 | 0.41–1.71 | 0.620 |
| EIAED | 4.0 | 1.43–6.57 | 5.0 | 3.54–6.46 | ||||||
| LEV vs. Any Other AED | ||||||||||
| LEV | 7.0 | 5.83–8.17 | 0.67 | 0.50–0.91 | 0.010 | 8.0 | 6.24–9.76 | 0.80 | 0.55–1.17 | 0.249 |
| Other AED | 4.0 | 2.79–5.21 | 7.0 | 3.32–10.68 | ||||||
| LEV vs. No LEV | ||||||||||
| LEV | 7.0 | 5.83–8.17 | 0.72 | 0.59–0.88 | 0.001 | 8.0 | 6.24–9.76 | 0.77 | 0.62–0.97 | 0.024 |
| No LEV | 4.5 | 3.86–5.14 | 6.0 | 5.46–6.54 | ||||||
Abbreviations: CI—confidence interval. HR—hazard ratio.