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. 2021 Jul 23;13(15):3699. doi: 10.3390/cancers13153699

Table 1.

Differentially expressed proteins upon treatment of GIST cells with IM/MK-4440 combination for 20 h.

GIST-T1 GIST-T1/829
Significantly Downregulated upon Treatment
ABCF2
ACACA
AGFG1
ARMC9
ATAD2
BMP2K
CASP7
CBX1
EIF1
EMC8
FADS2
FBN1
HMGCS1
HN1
HSBP1
IRF2BP2
KIF11
KPNA2
LSM14B
MAGT1
MKI67
NAV1
ODC1
PFN2
PRKCI
PRRC2A
RRM2
SEC62
SLC4A1AP
SPRY4
SQLE
SQSTM1
TACC3
TAX1BP3
TCAF1
TGFB1I1
TPX2
TYMS
ZFYVE16
ZPR1
ASAH1
ODC1
PTGS2
RAC2
RPL35A
SPAG5
TCAF1
Significantly Upregulated upon Treatment
ATP5D
BANF1
DERL1
GSTM2
H1FX
HIST1H1C
HIST1H4A
MRPL22
NDUFA4
NDUFS4
PBXIP1
PDCD4
TMEM109
ATP5D
HMGCR
ITM2C
NDUFAB1
PDCD4