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. 2021 Jul 26;13(15):3740. doi: 10.3390/cancers13153740

Figure 1.

Figure 1

Factors causing the development and progression of NAFLD-related HCC and other etiologies causing HCC aside from NAFLD. Abbreviations: DEN: diethylnitrosamine; ECM: extracellular matrix proteins; HCC: hepatocellular carcinoma; HSC: hepatic stellate cell; NAFLD: nonalcoholic fatty liver disease; NASH: nonalcoholic steatohepatitis.