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. 2021 Jul 26;13(15):3740. doi: 10.3390/cancers13153740

Figure 2.

Figure 2

Transcriptional and post-transcriptional factors mediated the progression of NAFLD and HCC. Abbreviations: AKT: protein kinase B; ApoB: apolipoprotein B; A1CF: catalytic polypeptide 1 complementation factor; DR5: death receptor 5; FOXO: Forkhead box; HIF-2α: hypoxia-inducible factor-2 alpha; HuR: human antigen R; LPIN: lipin; mTOR: mechanistic target of rapamycin; PI3K: phosphoinositide 3-kinase; PPARs: peroxisome prolifera-tor-activated receptors; SFR10: splicing factor, arginine/serine-rich 10; SREBP-1: sterol regulatory element-binding transcription factor-1; TGF-β: transforming growth factor-beta.