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. 2021 Jul 21;13(15):3661. doi: 10.3390/cancers13153661

Figure 3.

Figure 3

Oncological survival in intrahepatic cholangiocarcinoma (A): Cancer-specific and overall survival. The median CSS was 30 months and the median OS 28 months, respectively. (B): Recurrence-free survival. The median RFS was 12 months. (C): Cancer-specific survival stratified by nerve fibers. The median CSS was 51 months in patients with NF compared to 27 months (p = 0.043 log rank). (D): Recurrence-free survival stratified by nerve fibers. The median RFS was 20 months in patients with NF compared to 8 months in patients without NF (p = 0.006 log rank). (E): Cancer-specific survival stratified by nerve fibers and pN category. The mean CSS was 89 months in patients with NF and negative lymph nodes, while the median CCS was 27 months (95% CI: 38–64) in patients with either positive lymph nodes or without NF but not both, and 10 months in patients with both positive lymph nodes and low NF (p = 0.001 log rank). (F): Recurrence-free survival stratified by nerve fibers and pN category. The median RFS was 36 months in patients with NF and negative lymph nodes, 10 months (95% CI: 8–82) in patients with either positive lymph nodes or no NF but not both, and 5 months in patients with both positive lymph nodes and no NF (p = 0.001 log rank). CI, confidence interval; CSS, cancer-specific survival; RFS, recurrence-free survival; OS, overall survival.