Table 1.
DSM-5 diagnostic criteria for major depressive disorder.
| # | Symptom criteria (Any 5+ for diagnosis) |
|---|---|
| 1 | Depressed mood |
| 1a | OR irritability in youth |
| 2 | Anhedonia OR loss of interest |
| 3 | Significant weight change OR appetite disturbance (increase OR decrease) |
| 3a | OR failure to achieve expected weight gains in youth |
| 4 | Sleep disturbance (hypersomnia OR insomnia) |
| 5 | Psychomotor disturbance (agitation OR retardation) |
| 6 | Fatigue OR loss of energy |
| 7 | Feelings of worthlessness OR excessive guilt |
| 8 | Diminished ability to concentrate |
| 9 | Recurrent thoughts of death OR suicidal ideation OR a suicide attempt |
a
May substitute alternative criteria in children and adolescents.