Table 1.
The gender composition, age at study entry and end, number and interval between clinical observations and psychostimulant medication use for each symptom course group.
| Symptom course groups | |||||
|---|---|---|---|---|---|
| Never affected | Improvers | Stable | Worsening | Tests of group differences | |
| Total number | 129 | 110 | 63 | 60 | - |
| Male Female |
79 (61%) 50 (39%) |
81 (74%) 29 (26%) |
44 (70%) 19 (30%) |
42 (70%) 18 (30%) |
2 =4.52 p = 0.21 |
| Age at baseline: mean (SD) years | 8.7 (3.0) | 8.2 (2.0) | 8.1 (2.4) | 7.6 (2.8) | F(3,358)=2.49, p=0.06 |
| Age at last observation | 13.3 (3.1) | 13.8 (2.7) | 12.6 (2.9) | 12.0 (3.1) | F(3,358)=6.75, p=0.0001 [Improvers=never affected]> [stable=worsening] |
| Clinical 2 assessments 3 4 or more | 38 (30%) | 25 (23%) | 24 (38%) | 19 (32%) | 2=6.64, p=0.36 |
| 29 (22%) | 22 (20%) | 13 (21%) | 15 (25%) | ||
| 62 (48%) | 63 (57%) | 26 (41%) | 26 (43%) | ||
| Inter-observation interval Mean (SD) years | 1.97 (0.9) | 2.16 (1.22) | 2.15 (1.08) | 2.02 (0.97) | F(3,358)=0.85, p=0.47 |
| Baseline inattention | 0.1 (0.5) | 6.2 (2.2) | 6.3 (2.9) | 2.3 (2.5) | F(3,358)=281, p<0.00001, Never affected <worsening <[stable=improvers] |
| Baseline hyperactivity-impulsivity | 0.1 (0.4) | 5.26 (2.7) | 4.6 (2.1) | 3.0 (3.1) | F(3,358)=109, p<0.00001, Never affected <worsening <[stable=improvers] |
| Intelligence quotient | 115 (16) | 108 (13) | 107 (16) | 106 (15) | F(3,358)=8.1, p<0.00001, Never affected >[worsening=stable=improvers] |
| Psychostimulant treatment during study | |||||
| None Intermittent Constant | NA | 23 (24%) | 19 (33%) | 15 (33%) | 2=3.97, p=0.41 |
| NA | 54 (56%) | 24 (41%) | 22 (49%) | ||
| NA | 19 (20%) | 15 (26%) | 8 (18%) | ||