. 2021 Aug 3;13(15):3914. doi: 10.3390/cancers13153914

Table 6.

MRI parameters and histologic percentage of collagen content of soft and hard adenomas of all adenomas.

Parameters	Tumor Consistency Group		p Value
Parameters	Soft Adenoma (n = 34)	Hard Adenoma (n = 15)	p Value
rT1	0.840 ± 0.077	0.854 ± 0.088	0.40 ^a
rT2	1.661 ± 0.453	1.580 ± 0.295	0.55 ^a
ADC (10⁻³ mm²/s)	0.832 ± 0.263	0.769 ± 0.201	0.47 ^a
v_e	0.221 ± 0.104	0.332 ± 0.124	<0.01 ^b
v_p	0.070 ± 0.084	0.040 ± 0.042	0.36 ^a
K^trans (/min)	0.601 ± 0.612	0.775 ± 0.401	0.02 ^a
k_ep (/min)	2.240 ± 1.691	2.641 ± 1.672	0.37 ^a
PCC (%)	6.62 ± 3.47	44.08 ± 15.14	<0.01 ^b

rT1: ratio of signal intensity on T1-weighted MRI; rT2: ratio of signal intensity on T2-weighted MRI; ADC: apparent diffusion coefficient; v_e: volume of extravascular extracellular space per unit volume of tissue; v_p: blood plasma volume per unit volume of tissue; K^trans: volume transfer constant between blood plasma and extravascular extracellular space; k_ep: rate constant between extravascular extracellular space and blood plasma; PCC: percentage of collagen content. Statistical tests used: ^a Mann–Whitney U test, ^b unpaird t-test.