Table 4.
Groups | Blood Glucose (mg/dL) | Insulin (uIU/mL) |
HbA1C (mmol/mol) | Fasting Serum C-Peptide (ng/mL) |
---|---|---|---|---|
Group 1 (Control) |
87.4 ± 1.9 | 25.1 ± 0.6 | 3.2 ± 0.3 | 4.2 ± 0.1 |
Group 2 (STZ) |
377.3 ± 4.0 * | 4.2 ± 0.3 * | 9.2 ± 0.2 * | 0.5 ± 0.06 * |
Group 3 (STZ and STG) |
141.6 ± 4.0 *# | 18.9 ± 1.3 *# | 5.0 ± 0.5 *# | 2.6 ± 0.3 *# |
Group 4 (STZ and STG/Cu) |
130.8 ± 3.8 *# | 19.8 ± 1.5 *# | 3.0 ± 0.2# | 3.3 ± 0.3 *# |
Group 5 (STZ and STG/Mg) |
128.98 ± 2.58 # | 20.58 ± 1.08 # | 3.1 ± 0.08 # | 3.80 ± 0.6 # |
Group 6 (STZ and STG/Zn) |
95.4 ± 2.9 # | 23.5 ± 0.6 # | 3.3 ± 0.5 # | 4.1 ± 0.4 # |
Group 7 (STZ and STG/Ca) |
110 ± 3.58 # | 22.39 ± 2.01 # | 4.05 ± 0.36 # | 2.50 ± 0.63 # |
Group 8 (STZ + STG/Cr) |
90.24 ± 3.68 # | 23.68 ± 1.88 # | 3.01 ± 0.69 # | 3.98 ± 0.87 # |
Group 9 (STZ and STG/Se) |
100.69 ± 2.69 # | 21.02 ± 1.69 # | 3.68 ± 0.39 # | 3.21 ± 0.63 # |
p-value | <0.001 (HS) | <0.001 (HS) | <0.001 (HS) | <0.001 (HS) |
Data are presented as mean ± SD. * Significant difference compared to control group; # Significant difference compared to STZ group. HS: highly significant.