| Abbreviation | Definition |
| ADCC | Antibody-dependent cell-mediated cytotoxicity |
| ADCs | Antibody-drug conjugates |
| AIDS | Acquired immunodeficiency syndrome |
| ALAS1 | 5-Aminolevulinate synthase 1 |
| AOCs | Antibody-oligonucleotide conjugates |
| ApoB | Apolipoprotein B |
| ASOs | Antisense oligonucleotides |
| ASGPR | Asialoglycoprotein receptor |
| CBSA | Cationic bovine serum albumin |
| CPPs | Cell penetrating peptides |
| DDS | Drug delivery systems |
| DNA | Deoxyribonucleic acid |
| dsAON | Double stranded antisense oligonucleotide |
| DsiRNAs | Dicer substrate siRNAs |
| EDV | EnGeneIC delivery vehicle |
| EGFR | Epidermal growth factor receptor |
| EPM | Exosomes and PEI matrix |
| ESCRT | Endosomal sorting complex required for transport |
| FA | Folic acid |
| FDA | Food and Drug Administration |
| GalNAc | N-Acetylgalactosamine |
| GAPDH | Glyceraldehyde-3-phosphate dehydrogenase |
| GSCs | Glioblastoma stem cells |
| GSTP | Glutathione-S-transferase P |
| HAO1 | Hydroxyacid Oxidase 1 |
| hATTR | Hereditary transthyretin amyloidosis |
| HIV-1 | Human immunodeficiency virus-1 |
| HLA-G | Human leukocyte antigen-G |
| hsiRNA | Hydrophobically modified siRNA |
| HSPs | Heat shock proteins |
| ICAM-1 | Intercellular adhesion molecule-1 |
| IgG | Immunoglobulin G |
| ILVs | Intraluminal vesicles |
| Lamp | Lysosomal-associated membrane protein |
| LNAs | Locked nucleic acids |
| LNPs | Lipid nanoparticles |
| LODER | Local Drug Eluter |
| miRNA | MicroRNA |
| mRNA | Messenger RNA |
| MSC | Mesenchymal Stem Cell |
| MVBs | Multivesicular bodies |
| PC | Phosphatidylcholine |
| PDAC | Pancreatic ductal adenocarcinoma |
| PEA | Phosphatidylethanolamine |
| PEG | Poly(ethylene glycol) |
| PEI | Polyethyleneimine |
| PK | Pharmacokinetics |
| PKN3 | Protein Kinase N3 |
| PMO | Phosphorodiamidate morpholino oligomer |
| PS | Phosphatidylserine |
| PSLs | PEG-stabilized liposomes |
| RIG-1 | Retinoic acid-inducible gene-1 |
| RNA | Ribonucleic acid |
| RNAi | RNA interference |
| RVG | Rabies virus glycoprotein |
| siRNA | Small interfering RNA |
| SM | Sphingomyelin |
| SNALP | Stable nucleic acid lipid particle |
| STAT3 | Signal transducer and activator of transcription 3 |
| TEM | Tetraspanin-enriched microdomain |
| TNBC | Triple-negative breast cancer |
| TTR | Transthyretin |
| VEGF | Vascular endothelial growth factor |