Table 1.
Geographical variation in total PBC pathology-based prevalence
| Data points, n (%)a | Case number, n (%) | Population, n (%) | Prevalence/million persons | IRR (95% CI) | aIRR (95% CI) | |
| State | ||||||
| QLD | 9 (21.4%) | 258 (15.9%) | 4,297,330 (22.8%) | 60.04 | 1.00 [reference] | 1.00 [reference] |
| NSW/ACT | 10 (23.8%) | 474 (29.2%) | 7,179,925 (38.0%) | 66.02 | 1.10 (0.95, 1.28) | 1.09 (0.94, 1.27) |
| VIC | 10 (23.8%) | 583 (35.9%) | 5,328,052 (28.2%) | 109.42 | 1.82 (1.57, 2.11) | 1.78 (1.54, 2.07) |
| SA | 8 (19.1%) | 232 (14.3%) | 1,591,722 (8.4%) | 145.75 | 2.43 (2.03, 2.90) | 2.39 (1.99, 2.87) |
| TAS | 5 (11.9%) | 75 (4.6%) | 494,154 (2.6%) | 151.77 | 2.53 (1.96, 3.27) | 2.61 (2.01, 3.38) |
| P < 0.001 | ||||||
| Region type | ||||||
| Regional | 32 (76.2%) | 765 (47.2%) | 4,375,269 (23.2%) | 174.85 | 1.00 [reference] | |
| Metro | 4 (9.5%) | 446 (27.5%) | 4,489,204 (23.8%) | 99.35 | 1.30 (1.16, 1.46) | |
| Capital | 6 (14.3%) | 411 (25.3%) | 10,031,219 (53.1%) | 40.97 | 1.23 (1.09, 1.39) | |
| Trend: | P < 0.001 | |||||
| Latitude (continuous) | 1.05 (1.04, 1.06) P < 0.001 | 1.05 (1.03, 1.06) P < 0.001 | ||||
| Latitude (quintiles) | ||||||
| −18.02, −27.59 | 9 (21.4%) | 272 (16.8%) | 4,083,429 (21.6%) | 66.61 | 1.00 [reference] | 1.00 [reference] |
| <-27.59, −33.85 | 8 (19.1%) | 272 (16.8%) | 3,894,929 (20.6%) | 69.83 | 1.05 (0.89, 1.24) | 1.06 (0.90, 1.26) |
| <-33.85, −35.33 | 8 (19.1%) | 364 (22.4%) | 4,162,546 (22.0%) | 87.45 | 1.31 (1.12, 1.54) | 1.27 (1.08, 1.49) |
| <-35.33, −37.75 | 8 (19.1%) | 190 (11.7%) | 2,324,882 (12.3%) | 81.72 | 1.23 (1.02, 1.48) | 1.27 (1.05, 1.54) |
| <-37.75, −42.72 | 9 (21.4%) | 524 (32.3%) | 4,425,397 (23.4%) | 118.41 | 1.78 (1.54, 2.06) | 1.71 (1.47, 1.99) |
| Trend: | P < 0.001 | P < 0.001 | ||||
| Sex | ||||||
| Male | 179 (11.0%) | 9,697,783 (49.4%) | 18.46 | 1.00 [reference] | 1.00 [reference] | |
| Female | 1,443 (89.0%) | 9,947,776 (50.6%) | 145.06 | 7.86 (6.73, 9.18) | 7.86 (6.73, 9.18) | |
| P < 0.001 | P < 0.001 | |||||
| Age | ||||||
| 0–39 | 79 (4.9%) | 10,044,474 (53.2%) | 7.87 | 0.11 (0.09, 0.15) | 0.11 (0.09, 0.15) | |
| 40–49 | 186 (11.5%) | 2,666,185 (14.1%) | 69.76 | 1.00 [reference] | 1.00 [reference] | |
| 50–59 | 378 (23.3%) | 2,412,864 (12.8%) | 156.66 | 2.25 (1.88, 2.68) | 2.27 (1.90, 2.70) | |
| 60–69 | 434 (26.8%) | 1,885,486 (10.0%) | 230.18 | 3.30 (2.78, 3.92) | 3.36 (2.83, 3.99) | |
| 70–79 | 335 (20.7%) | 1,122,231 (5.9%) | 298.51 | 4.28 (3.58, 5.12) | 4.36 (3.64, 5.21) | |
| 80–109 | 210 (13.0%) | 758,655 (4.0%) | 276.81 | 3.97 (3.26, 4.83) | 3.99 (3.28, 4.87) | |
| Trend: | P < 0.001 | P < 0.001 |
Bold indicates statistical significance.
Analyses by Poisson regression, estimating an IRR (95% CI). Adjusted models adjusted for region type.
a
Two-digit postcode regions within each state.