Table 2.

Criteria according to lesion pathophysiology and onset mode.

Classification		Criterion
MSD Type	Onset Mode	Inflammation	Tissue	Tissue Regeneration and Outcome
0	Late	Acute	Healthy	Complete tissue regeneration (regeneration without irreversible cellular changes)
1	Sudden	Acute	Healthy	Complete tissue regeneration without fibrosis
2	Sudden	Chronic	Healthy or Altered	Fibrosis/cell death/progressive chronic inflammation
3	Gradual	Chronic	Altered	Fibrosis/loss of function/tissue granulation Neuropathic pain/neural fibrosis