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Therapeutic materials that mediate autophagy in skin barrier-related skin diseases.
| Skin Diseases | Therapeutic Materials | Effects on Autophagy | Consequent Changes | Refs. |
|---|---|---|---|---|
| Skin squamous cell carcinoma | Chloroquine | ↓ | Apoptosis ↑ | [96,97,98] |
| Melanoma | Dabrafenib | ↓ | Antitumor activity ↑ | [108] |
| Chloroquine | ↓ | Antitumor activity ↑ | [109,110,111,112,113] | |
| Acne | Rapamycin | ↑ | Lipogenesis ↓, Fatty acid synthesis genes ↓ | [117] |
↓: Autophagy inhibition, ↑: Autophagy induction.
