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Tissue microarray (TMA)-based immunohistochemistry analysis of ZNF677 and phospho-AKT in papillary thyroid carcinoma (PTC) patients. PTC TMA spots showing loss of ZNF677 (A) and low expression of phospho-AKT (D). In contrast, another set of TMA spots shows normal expression of ZNF677 (B) and high expression of phospho-AKT (C). 20 X/0.70 objective on an Olympus BX 51 microscope. (Olympus America Inc., Center Valley, PA, USA).
