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. 2021 Jul 23;22(15):7855. doi: 10.3390/ijms22157855

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Functionalized strategies for polymeric delivery system. (a) The structure of polymeric delivery system; (b) NPs with PLGA and DOTAP hybridization (reproduced with permission from copyright 2020 American Chemical Society); (c) DNA nanotechnology-based strategy via the cascade hybridization chain reaction (HCR) of DNA hairpins in polymeric nanoframework (reproduced with permission from copyright 2021 Springer Nature limited); (d) biocompatible pH-responsive NPs synthesized by acetylation of cyclodextrins (CDs) and their polymers (reproduced with permission from copyright 2020 Wiley-VCH); (e) N-acetylgalactosamine functionalized mixed micellar NPs (Reproduced with permission from copyright 2012 Elsevier B.V.); (f) polymeric NPs as miRNA carriers together with a shear-thinning hydrogel to encapsulate the miNPs (reproduced with permission from copyright 2019 American Chemical Society).