Table 3.

Association between tumour size and insufficient axes in surgery-naïve patients.

Total	1–10 mm	11–20 mm	21–30 mm	31–40 mm	>40 mm	P value
Adrenal axis, n = 103*	1/8 (13%)	2/20 (9%)	14/39 (36%)	12/31 (39%)	4/5 (80%)	0.003
Thyroid axis, n = 104	3/13 (23%)	5/20 (25%)	21/37 (57%)	21/29 (72%)	4/5 (80%)	<0.001
Gonadal axis, n = 107	4/14 (29%)	7/20 (35%)	29/39 (74%)	28/30 (95%)	4/4 (100%)	<0.001

*patients with Cushing’s disease were excluded.