TABLE 1.
The levels of fasting blood-glucose and insulin to calculate the HOMA-IR and HOMA-ISI after metformin treatment.
| Group | Fasting blood-glucose (mmol/L) | Insulin (mIU/L) | HOMA-IR | HOMA-ISI |
|---|---|---|---|---|
| Ctrl | 2.875 ± 0.350 | 0.096 ± 0.006 | 0.012 ± 0.001 | 3.763 ± 0.263 |
| HFD | 4.500 ± 0.844 | 0.151 ± 0.016 | 0.029 ± 0.003 a | 1.611 ± 0.198 b |
| HFD+Met | 4.900 ± 0.424 | 0.091 ± 0.005 | 0.020 ± 0.001 c | 2.285 ± 0.099 c |
| F | 3.403 | 0.955 | 2.958 | 0.626 |
| P | 0.079 | 0.421 | 0.103 | 0.557 |
Homeostatic model assessment for insulin resistance (HOMA-IR) index, Homeostatic model assessment for insulin sensitivity index (HOMA-ISI). Data presents mean ± SEM; n = 6.
a
p < 0.01.
b
p < 0.001, HFD group versus control group.
c
p < 0.05, Metformin+HFD-fed group versus HFD group, respectively, using one-way ANOVA.