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. 2021 Jul 23;12:689111. doi: 10.3389/fphar.2021.689111

TABLE 2.

The levels of fasting blood-glucose and insulin to calculate the HOMA-IR and HOMA-ISI after knockdown of TFEB.

Group Fasting blood-glucose (mmol/L) Insulin (mIU/L) HOMA-IR HOMA-ISI
HM+SC 4.767 ± 0.536 0.095 ± 0.013 0.020 ± 0.001 2.295 ± 0.172
HM+TS 6.375 ± 1.321 0.132 ± 0.024 0.034 ± 0.002 a 1.336 ± 0.089 a
T 0.989 1.255 4.674 5.389
P 0.368 0.265 0.006 0.003

Homeostatic model assessment for insulin resistance (HOMA-IR) index, Homeostatic model assessment for insulin sensitivity index (HOMA-ISI). Data presents mean ± SEM; n = 6.

a

p < 0.01, HFD+Met+TFEB shRNA (HM+TS) group versus HFD+Met+Scramble control (HM+SC), respectively, using t-test.