Table 3.
Embryonic craniofacial development after treatment of pregnant rats with khat: day 12 experiment.
| Treatment group | Percent retarded development | |||
|---|---|---|---|---|
| Optic system | Olfactory system | Branchial bars | Maxillary process | |
| Control | 0 | 1.7 | 4 | 4 |
| K250 | 0 | 3 | 5 | 6 |
| K500 | 5.6a, b | 4.1 | 7 | 8 |
| K750 | 8.2a,b | 10a,b | 10a,b | 10a,b |
| Ad libitum control | 1.3 | 1.5 | 4 | 4 |
K250: khat extract 250 mg/kg; K500: khat extract 500 mg/kg; K750: khat extract 250 mg/kg; results are summarized as percentages of retarded development; a,bsignificantly different (p < 0.05) from ad libitum control and pair-fed control groups; chi-square.