Table 2.
Standard pairwise meta-analysis and network meta-analysis of excess weight loss following metabolic surgery
| Time point | Intervention | Comparator | No. of direct comparison studies | Pairwise meta-analysis (SMD)* | Between-study variance (MA) | Network meta-analysis (SMD)* | Between-study variance (NMA) |
|---|---|---|---|---|---|---|---|
| 1 year | RYGB | SG | 9 |
0.06 (− 0.09, 0.22) |
0.200 |
1.67 (− 0.89, 4.24) |
0.202 |
| RYGB | OAGB | 2 |
1.76 (− 0.77, 0.77) |
0.210 |
4.35 (1.30, 7.40) |
0.005 | |
| SG | OAGB | 2 |
1.21 (− 0.64, 3.13) |
0.233 |
2.68 (0.16, 5.21) |
0.037 | |
| 2 years | RYGB | SG | 5 |
0.05 (− 0.024, 0.14) |
0.347 |
1.37 (− 2.31, 5.06) |
0.465 |
| RYGB | OAGB | 3 |
1.00 (− 0.63, 2.63) |
0.222 |
3.84 (0.47, 7.22) |
0.026 | |
| SG | OAGB | 2 |
1.26 (− 1.01, 3.54) |
0.309 |
2.47 (− 0.85, 5.79) |
0.144 | |
| 3–5 years | RYGB | SG | 7 |
− 0.28 (− 0.49, − 0.07) |
0.024 |
− 7.19 (− 10.88, − 3.51) |
< 0.001 |
| RYGB | OAGB | 1 | N/A | - |
0.85 (− 3.24, 4.93) |
0.685 | |
| SG | OAGB | 2 |
1.78 (− 1.22, 4.78) |
0.301 |
8.04 (3.98, 12.10) |
< 0.001 |
*Values in parentheses are 95% confidence intervals. A standardised mean difference (SMD) greater than 0.00 favours the comparator (more EWL with comparator than with intervention); a SMD of less than 0.00 favours intervention (less EWL with comparator than with intervention).
MA standard pairwise meta-analysis, NMA network meta-analysis.