Table 2.
Coagulation, inflammatory and ROTEM parameters of total cohort and sub cohorts with and without cavitary lesions on CT-scan.
| Cohort (N = 39) | |||||||
|---|---|---|---|---|---|---|---|
| Median | [IQR] | Cavitations | |||||
| Yes (N = 22) | No (N = 17) | p-value | |||||
| Median | [IQR] | Median | [IQR] | ||||
| Laboratory variables (normal values) | |||||||
| Haemoglobin (12.5–17.2 g/dL) | 10.1 | [8.5–11.2] | 10.1 | [8.7–11.9] | 9.50 | [8.1–10.9] | 0.34 |
| White blood cells (3.5–10.5/nl) | 19.3 | [16.3–28.8] | 21.4 | [17–30.6] | 19.3 | [14.9–28.8] | 0.63 |
| Platelet count (150–370/nl) | 186 | [131.3–314] | 190 | [128–254.0] | 186 | [121–324] | 0.68 |
| Prothrombin time (70–130%) | 71 | [62–82.7] | 70 | [51–82.5] | 74.5 | [67.25–85] | 0.27 |
| INR (0.9–1.25) | 1.35 | [1.2–1.6] | 1.5 | [1.3–1.7] | 1.29 | [1.1–1.4] | 0.12 |
| PTT (26–40 s) | 45.7 | [40–56.1] | 45.1 | [40.3–585] | 46.1 | [39.1–56] | 0.75 |
| Fibrinogen (1.6–4 g/l) | 6.6 | [4.7–7.8] | 6.4 | [4.7–7.2] | 6.1 | [4.6–7.9] | 0.38 |
| D-dimers (< 0.5 mg/l) | 8.4 | [3.9–17.2] | 10 | [3.6–18.6] | 8.2 | [3.9–11.6] | 0.48 |
| Procalcitonin (0.5 µg/l) | 7.6 | [1.9–15.7] | 7.9 | [1–16.9] | 7.6 | [3.1–18.9] | 0.86 |
| CRP (< 0.5 mg/l) | 312.9 | [207.1–344.1] | 305.6 | [181.8–352.5] | 333.9 | [215.6–344.4] | 0.56 |
| IL-6 (< 7 ng/l) | 558.6 | [180.2–1921.7] | 567.2 | [163.8–18600] | 550 | [179.5–1894.5] | 0.97 |
| Ferritin (30–400 µg/l) | 2619.8 | [1557–7111.9] | 2621 | [1155.7–8068.8] | 2113.3 | [1710.9–6392.2] | 0.50 |
| Ristocetin-Co-factor (%) | 349 | [204–404] | 349 | [179.5–429.5] | 291 | [259–401.5] | 0.78 |
| vWillebrand antigen (%) | 391 | [283.5–400] | 394 | [266.5–400] | 368.5 | [278.7–400] | 0.96 |
| Factor VIII (50–150%) | 258 | [190.5–319.5] | 259 | [212.2–293.5] | 245 | [153.2–340] | 0.71 |
| EXTEM MCF (mm) | 75 | [70–78] | 74.5 | [69.7–78.2] | 76 | [70.5–77.5] | 0.89 |