. Author manuscript; available in PMC: 2021 Nov 23.

Published in final edited form as: Angew Chem Int Ed Engl. 2020 Sep 17;59(48):21634–21639. doi: 10.1002/anie.202007953

Table 2.

Substrate scope for Mb(F43L,H64A,V68G,I107V)-catalyzed intramolecular cyclopropanation of homoallylic α-diazoacetats ^[a]

^[a]

Reaction conditions: 2.5 mM substrate, Mb(F43L,H64A,V68G,I107V)-expressing E.coli (OD₆₀₀ = 20) in KPi buffer (50 mM, pH 7), 80 mL-scale, RT, 2 hrs.

^[b]

Product conversion as determined by GC. Yields of isolated products are reported in brackets. Errors are within 10%.

^[c]

Using OD₆₀₀ = 60.

^[d]

Using 1 mM substrate, 200 mL-scale.