Table 1.
P value* | AUC** |
---|---|
a. First cohort | |
≤ 1.00E−10 | 0.8462 |
≤ 1.00E−09 | 0.8487 |
≤ 1.00E−08 | 0.8518 |
≤ 1.00E−07 | 0.8565 |
≤ 1.00E−06 | 0.8604 |
≤ 1.00E−05 | 0.8607 |
≤ 1.00E−04 | 0.8590 |
≤ 0.001 | 0.8561 |
≤ 0.01 | 0.8546 |
≤ 0.05 | 0.8502 |
≤ 0.1 | 0.8508 |
≤ 0.2 | 0.8530 |
≤ 0.5 | 0.8563 |
≤ 1 | 0.8579 |
b. Switched cohort | |
≤ 1.00E−10 | 0.8576 |
≤ 1.00E−09 | 0.8589 |
≤ 1.00E−08 | 0.8588 |
≤ 1.00E−07 | 0.8609 |
≤ 1.00E−06 | 0.8633 |
≤ 1.00E−05 | 0.8654 |
≤ 1.00E−04 | 0.8618 |
≤ 0.001 | 0.8555 |
≤ 0.01 | 0.8470 |
≤ 0.05 | 0.8441 |
≤ 0.1 | 0.8446 |
≤ 0.2 | 0.8467 |
≤ 0.5 | 0.8521 |
≤ 1 | 0.8533 |
*The P values are based on the statistics of the PRS training cohort.
**The AUCs are the PRS performances in the independent testing cohort.