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. 2021 Aug 6;11:16013. doi: 10.1038/s41598-021-94994-9

Table 1.

The AUCs of different cutoffs of T1D association P values.

P value* AUC**
a. First cohort
 ≤ 1.00E−10 0.8462
 ≤ 1.00E−09 0.8487
 ≤ 1.00E−08 0.8518
 ≤ 1.00E−07 0.8565
 ≤ 1.00E−06 0.8604
 ≤ 1.00E−05 0.8607
 ≤ 1.00E−04 0.8590
 ≤ 0.001 0.8561
 ≤ 0.01 0.8546
 ≤ 0.05 0.8502
 ≤ 0.1 0.8508
 ≤ 0.2 0.8530
 ≤ 0.5 0.8563
 ≤ 1 0.8579
b. Switched cohort
 ≤ 1.00E−10 0.8576
 ≤ 1.00E−09 0.8589
 ≤ 1.00E−08 0.8588
 ≤ 1.00E−07 0.8609
 ≤ 1.00E−06 0.8633
 ≤ 1.00E−05 0.8654
 ≤ 1.00E−04 0.8618
 ≤ 0.001 0.8555
 ≤ 0.01 0.8470
 ≤ 0.05 0.8441
 ≤ 0.1 0.8446
 ≤ 0.2 0.8467
 ≤ 0.5 0.8521
 ≤ 1 0.8533

*The P values are based on the statistics of the PRS training cohort.

**The AUCs are the PRS performances in the independent testing cohort.