Table 3.
Novel loci associated with low PRS T1D.
| CHR | BP (hg38) | SNP | dbSNP | allele | allele_Frq | Quality Score (r2) | Genotyped | n | OR | L95 | U95 | P | n | OR | L95 | U95 | P | Func.refGene | Gene.refGene |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low PRS cases versus low PRS controls | All cases versus all controls in the cohort | ||||||||||||||||||
| a. First cohort | |||||||||||||||||||
| 2 | 1,07,27,877 | chr2:10727877:C:T | rs147458998 | T | 0.00203 | 0.718 | Imputed | 6118 | 11.06 | 4.818 | 25.4 | 1.45E−08 | 9450 | 3.201 | 1.508 | 6.795 | 0.002454 | Intronic | ATP6V1C2 |
| 2 | 1,71,26,012 | chr2:17126012:C:T | rs56806432 | T | 0.03445 | 0.97878 | Imputed | 6118 | 1.936 | 1.539 | 2.437 | 1.74E−08 | 9450 | 1.149 | 0.976 | 1.352 | 0.09531 | Intergenic | FAM49A;RAD51AP2 |
| 2 | 1,71,59,712 | chr2:17159712:C:A | rs16983255 | A | 0.03454 | 0.97987 | Imputed | 6118 | 1.916 | 1.523 | 2.411 | 2.85E−08 | 9450 | 1.142 | 0.9704 | 1.343 | 0.1101 | Intergenic | FAM49A;RAD51AP2 |
| 2 | 1,71,59,927 | chr2:17159927:C:T | rs60975145 | T | 0.03448 | 0.9799 | Imputed | 6118 | 1.927 | 1.532 | 2.425 | 2.17E−08 | 9450 | 1.148 | 0.9755 | 1.351 | 0.09667 | Intergenic | FAM49A;RAD51AP2 |
| 2 | 5,15,13,429 | chr2:51513429:G:A | rs28958299 | A | 0.00609 | 0.98423 | Imputed | 6118 | 3.4 | 2.194 | 5.269 | 4.39E−08 | 9450 | 1.527 | 1.05 | 2.223 | 0.02693 | ncRNA_intronic | LOC730100 |
| 2 | 5,14,87,374 | chr2:51487374:C:CA | CA | 0.0063 | 0.98739 | Imputed | 6118 | 3.415 | 2.201 | 5.298 | 4.25E−08 | 9450 | 1.566 | 1.079 | 2.275 | 0.0184 | |||
| 2 | 5,15,04,453 | chr2:51504453:C:T | rs57623361 | T | 0.00667 | 0.98795 | Imputed | 6118 | 3.251 | 2.129 | 4.964 | 4.75E−08 | 9450 | 1.532 | 1.07 | 2.192 | 0.0198 | ncRNA_intronic | LOC730100 |
| 2 | 5,15,31,113 | chr2:51531113:T:A | rs28957091 | A | 0.00679 | 0.98915 | Imputed | 6118 | 3.408 | 2.239 | 5.188 | 1.07E−08 | 9450 | 1.611 | 1.124 | 2.308 | 0.009372 | ncRNA_intronic | LOC730100 |
| 2 | 5,15,28,593 | chr2:51528593:T:C | rs1406418 | C | 0.00716 | 0.99126 | Imputed | 6118 | 3.166 | 2.094 | 4.789 | 4.74E−08 | 9450 | 1.531 | 1.079 | 2.172 | 0.01703 | ncRNA_intronic | LOC730100 |
| 2 | 5,15,30,016 | chr2:51530016:T:G | rs28958318 | G | 0.0073 | 0.99201 | Imputed | 6118 | 3.205 | 2.122 | 4.84 | 3.10E−08 | 9450 | 1.579 | 1.113 | 2.24 | 0.01039 | ncRNA_intronic | LOC730100 |
| 2 | 5,15,20,595 | chr2:51520595:C:T | rs28957085 | T | 0.00601 | 0.99376 | Imputed | 6118 | 3.575 | 2.31 | 5.533 | 1.09E−08 | 9450 | 1.616 | 1.113 | 2.346 | 0.01167 | ncRNA_intronic | LOC730100 |
| 2 | 5,14,86,782 | chr2:51486782:AG:A | A | 0.00593 | 0.99402 | Imputed | 6118 | 3.445 | 2.213 | 5.364 | 4.30E−08 | 9450 | 1.476 | 1.01 | 2.156 | 0.04423 | ncRNA_intronic | LOC730100 | |
| 2 | 5,15,25,890 | chr2:51525890:A:G | rs1528792 | G | 0.00684 | 0.99484 | Imputed | 6118 | 3.27 | 2.159 | 4.951 | 2.18E−08 | 9450 | 1.529 | 1.075 | 2.174 | 0.01814 | ncRNA_intronic | LOC730100 |
| 2 | 5,15,28,054 | chr2:51528054:T:C | rs28957087 | C | 0.00735 | 0.99609 | Imputed | 6118 | 3.306 | 2.195 | 4.979 | 1.04E−08 | 9450 | 1.607 | 1.135 | 2.276 | 0.007525 | ncRNA_intronic | LOC730100 |
| 9 | 1,42,29,050 | chr9:14229050:G:C | rs10961435 | C | 0.00389 | 0.95755 | Imputed | 6118 | 4.762 | 2.753 | 8.237 | 2.39E−08 | 9450 | 1.806 | 1.103 | 2.957 | 0.01885 | Intronic | NFIB |
| 10 | 4,42,60,591 | chr10:44260591:C:T | rs746298 | T | 0.00446 | 0.98941 | Imputed | 6118 | 4.175 | 2.552 | 6.83 | 1.26E−08 | 9450 | 2.304 | 1.485 | 3.576 | 0.000197 | Intergenic | LINC00841;C10orf142 |
| 10 | 6,06,64,647 | chr10:60664647:T:C | rs1816797 | C | 0.00183 | 0.93498 | Imputed | 6118 | 8.974 | 4.087 | 19.7 | 4.55E−08 | 9450 | 4.188 | 2.04 | 8.599 | 9.52E−05 | Intronic | ANK3 |
| 12 | 3,46,99,338 | chr12:34699338:G:T | rs12424461 | T | 0.00231 | 0.85309 | Imputed | 6118 | 8.528 | 4.101 | 17.73 | 9.54E−09 | 9450 | 2.127 | 1.105 | 4.094 | 0.02396 | Intergenic | ALG10;NONE |
| b. Switched cohort | |||||||||||||||||||
| 2 | 6,24,48,472 | chr2:62448472:C:T | rs78389245 | T | 0.00223 | 0.93017 | Imputed | 6460 | 6.453 | 3.353 | 12.42 | 2.37E−08 | 9465 | 2.246 | 1.248 | 4.041 | 0.006953 | Intergenic | B3GNT2;TMEM17 |
| 2 | 6,24,42,411 | chr2:62442411:A:G | rs75610843 | G | 0.00349 | 0.96936 | Imputed | 6460 | 5.023 | 2.83 | 8.917 | 3.54E−08 | 9465 | 2.114 | 1.278 | 3.498 | 0.003576 | Intergenic | B3GNT2;TMEM17 |
| 2 | 6,24,46,036 | chr2:62446036:C:T | rs76505469 | T | 0.0031 | 0.96962 | Imputed | 6460 | 5.655 | 3.117 | 10.26 | 1.20E−08 | 9465 | 1.959 | 1.156 | 3.319 | 0.01245 | Intergenic | B3GNT2;TMEM17 |
| 2 | 6,24,40,366 | chr2:62440366:C:T | rs75921605 | T | 0.00346 | 0.97057 | Imputed | 6460 | 5.023 | 2.83 | 8.917 | 3.54E−08 | 9465 | 2.114 | 1.278 | 3.498 | 0.003576 | Intergenic | B3GNT2;TMEM17 |
| 2 | 7,03,52,234 | chr2:70352234:A:G | rs116081627 | G | 0.002 | 0.91477 | Imputed | 6460 | 7.679 | 3.755 | 15.7 | 2.34E−08 | 9465 | 1.911 | 1 | 3.651 | 0.05001 | Intergenic | FAM136A;TGFA |
| 3 | 4,89,51,134 | chr3:48951134:T:C | rs143836109 | C | 0.00397 | 0.58298 | Imputed | 6460 | 4.986 | 2.801 | 8.875 | 4.77E−08 | 9465 | 1.782 | 1.059 | 2.999 | 0.02969 | Intronic | ARIH2 |
| 4 | 8,83,57,077 | chr4:88357077:T:C | rs76377119 | C | 0.002 | 0.71507 | Imputed | 6460 | 9.545 | 4.389 | 20.76 | 1.26E−08 | 9465 | 4.076 | 1.927 | 8.622 | 0.000237 | Intergenic | LOC105369192;HERC6 |
| 4 | 14,15,56,946 | chr4:141556946:C:T | rs72615940 | T | 0.00275 | 0.95975 | Imputed | 6460 | 6.361 | 3.301 | 12.26 | 3.25E−08 | 9465 | 2.651 | 1.469 | 4.784 | 0.001204 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,57,792 | chr4:141557792:T:C | rs115762557 | C | 0.00279 | 0.96694 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,58,035 | chr4:141558035:A:C | rs72615945 | C | 0.00278 | 0.96769 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,58,497 | chr4:141558497:G:GATTTTCA | GATTTTCA | 0.00278 | 0.96769 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | |||
| 4 | 14,15,58,842 | chr4:141558842:C:T | rs72615950 | T | 0.00278 | 0.96771 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,59,253 | chr4:141559253:G:A | rs72615951 | A | 0.00278 | 0.96771 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,59,260 | chr4:141559260:G:A | rs72615952 | A | 0.00278 | 0.96771 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,57,845 | chr4:141557845:T:A | rs77083164 | A | 0.00278 | 0.96773 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,57,678 | chr4:141557678:A:G | rs75736694 | G | 0.00278 | 0.96774 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,58,749 | chr4:141558749:G:A | rs72615948 | A | 0.00278 | 0.96774 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,57,600 | chr4:141557600:A:G | rs72615942 | G | 0.00278 | 0.96775 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,58,193 | chr4:141558193:G:C | rs72615946 | C | 0.00278 | 0.96775 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,58,199 | chr4:141558199:C:T | rs72615947 | T | 0.00278 | 0.96775 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,57,291 | chr4:141557291:T:C | rs72615941 | C | 0.00278 | 0.96776 | Imputed | 6460 | 6.046 | 3.166 | 11.54 | 4.96E−08 | 9465 | 2.474 | 1.368 | 4.475 | 0.002725 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,56,501 | chr4:141556501:C:T | rs17007424 | T | 0.00256 | 0.97308 | Imputed | 6460 | 6.361 | 3.301 | 12.26 | 3.25E−08 | 9465 | 2.454 | 1.35 | 4.462 | 0.003252 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,56,393 | chr4:141556393:A:G | rs72615939 | G | 0.00257 | 0.97583 | Imputed | 6460 | 6.361 | 3.301 | 12.26 | 3.25E−08 | 9465 | 2.454 | 1.35 | 4.462 | 0.003252 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,56,881 | chr4:141556881:C:T | rs200157898 | T | 0.00257 | 0.97584 | Imputed | 6460 | 6.361 | 3.301 | 12.26 | 3.25E−08 | 9465 | 2.454 | 1.35 | 4.462 | 0.003252 | Intergenic | LINC02432;IL15 |
| 4 | 14,15,57,024 | chr4:141557024:TACTC:T | T | 0.00257 | 0.97591 | Imputed | 6460 | 6.361 | 3.301 | 12.26 | 3.25E−08 | 9465 | 2.454 | 1.35 | 4.462 | 0.003252 | Intergenic | LINC02432;IL15 | |
| 5 | 15,94,80,234 | chr5:159480234:C:T | rs117952033 | T | 0.00138 | 0.83707 | Imputed | 6460 | 14.31 | 5.602 | 36.55 | 2.68E−08 | 9465 | 4.707 | 1.862 | 11.9 | 0.001062 | Intergenic | LINC01845;LINC01847 |
| 5 | 15,94,99,811 | chr5:159499811:C:T | rs10515798 | T | 0.00148 | 0.84382 | Imputed | 6460 | 14.31 | 5.602 | 36.55 | 2.68E−08 | 9465 | 4.707 | 1.862 | 11.9 | 0.001062 | Intergenic | LINC01845;LINC01847 |
| 6 | 17,02,83,857 | chr6:170283857:C:T | rs3734776 | T | 0.00695 | 0.93794 | Imputed | 6460 | 3.602 | 2.351 | 5.518 | 3.87E−09 | 9465 | 1.912 | 1.334 | 2.741 | 0.000422 | Exonic | DLL1 |
| 6 | 17,02,88,217 | chr6:170288217:C:T | rs3818115 | T | 0.00634 | 0.93938 | Imputed | 6460 | 3.633 | 2.336 | 5.649 | 1.02E−08 | 9465 | 1.819 | 1.255 | 2.638 | 0.001589 | Intronic | DLL1 |
| 6 | 17,02,84,744 | chr6:170284744:C:T | rs2273214 | T | 0.00632 | 0.94094 | Imputed | 6460 | 3.633 | 2.336 | 5.649 | 1.02E−08 | 9465 | 1.819 | 1.255 | 2.638 | 0.001589 | Intronic | DLL1 |
| 6 | 17,02,90,297 | chr6:170290297:C:T | rs3823301 | T | 0.00644 | 0.94127 | Imputed | 6460 | 3.639 | 2.356 | 5.619 | 5.74E−09 | 9465 | 1.791 | 1.241 | 2.585 | 0.001843 | UTR5 | DLL1 |
| 6 | 17,02,87,112 | chr6:170287112:A:C | rs3800238 | C | 0.00632 | 0.94131 | Imputed | 6460 | 3.633 | 2.336 | 5.649 | 1.02E−08 | 9465 | 1.819 | 1.255 | 2.638 | 0.001589 | Intronic | DLL1 |
| 6 | 17,02,87,178 | chr6:170287178:C:A | rs3800237 | A | 0.00861 | 0.94352 | Imputed | 6460 | 3.085 | 2.12 | 4.49 | 3.98E−09 | 9465 | 1.543 | 1.126 | 2.115 | 0.007003 | Intronic | DLL1 |
| 7 | 7,20,10,707 | chr7:72010707:G:C | rs118182411 | C | 0.00376 | 0.93903 | Imputed | 6460 | 4.074 | 2.474 | 6.71 | 3.42E−08 | 9465 | 1.513 | 0.9562 | 2.393 | 0.07696 | Intronic | CALN1 |
| 7 | 8,93,18,777 | chr7:89318777:C:T | rs77205087 | T | 0.00582 | 0.9747 | Imputed | 6460 | 3.447 | 2.238 | 5.308 | 1.94E−08 | 9465 | 1.321 | 0.8943 | 1.951 | 0.1619 | Intronic | ZNF804B |
| 7 | 8,93,09,079 | chr7:89309079:C:T | rs76060515 | T | 0.00578 | 0.97724 | Imputed | 6460 | 3.447 | 2.238 | 5.308 | 1.94E−08 | 9465 | 1.321 | 0.8943 | 1.951 | 0.1619 | Intronic | ZNF804B |
| 7 | 10,08,14,253 | chr7:100814253:G:A | rs3890144 | A | 0.00757 | 0.95297 | Imputed | 6460 | 3.061 | 2.066 | 4.537 | 2.47E−08 | 9465 | 1.352 | 0.959 | 1.906 | 0.0853 | Intronic | EPHB4 |
| 7 | 10,07,99,808 | chr7:100799808:C:T | rs60224425 | T | 0.00756 | 0.95354 | Imputed | 6460 | 3.021 | 2.043 | 4.467 | 3.01E−08 | 9465 | 1.403 | 1 | 1.966 | 0.04969 | Intergenic | ZAN;EPHB4 |
| 9 | 11,02,69,080 | chr9:110269080:T:G | rs10816957 | G | 0.00712 | 0.94616 | Imputed | 6460 | 3.054 | 2.063 | 4.52 | 2.44E−08 | 9465 | 1.306 | 0.9282 | 1.838 | 0.1254 | Intergenic | TXN;TXNDC8 |
| 12 | 3,36,97,680 | chr12:33697680:T:C | rs11052850 | C | 0.00691 | 0.99026 | Imputed | 6460 | 2.758 | 1.918 | 3.966 | 4.37E−08 | 9465 | 1.131 | 0.8173 | 1.565 | 0.4581 | Intergenic | SYT10;ALG10 |
| 12 | 3,36,97,996 | chr12:33697996:G:A | rs1352395 | A | 0.0069 | 0.9906 | Imputed | 6460 | 2.758 | 1.918 | 3.966 | 4.37E−08 | 9465 | 1.131 | 0.8173 | 1.565 | 0.4581 | Intergenic | SYT10;ALG10 |
| 12 | 3,36,95,324 | chr12:33695324:G:A | rs12228218 | A | 0.00689 | 0.9914 | Imputed | 6460 | 2.758 | 1.918 | 3.966 | 4.37E−08 | 9465 | 1.131 | 0.8173 | 1.565 | 0.4581 | Intergenic | SYT10;ALG10 |
| 12 | 3,36,80,534 | chr12:33680534:G:A | rs4142676 | A | 0.00691 | 0.99149 | Imputed | 6460 | 2.758 | 1.918 | 3.966 | 4.37E−08 | 9465 | 1.131 | 0.8173 | 1.565 | 0.4581 | Intergenic | SYT10;ALG10 |
| 12 | 3,36,93,014 | chr12:33693014:T:C | rs11052843 | C | 0.00689 | 0.99193 | Imputed | 6460 | 2.758 | 1.918 | 3.966 | 4.37E−08 | 9465 | 1.131 | 0.8173 | 1.565 | 0.4581 | Intergenic | SYT10;ALG10 |
| 12 | 3,36,97,208 | chr12:33697208:T:C | rs2087269 | C | 0.00689 | 0.992 | Imputed | 6460 | 2.758 | 1.918 | 3.966 | 4.37E−08 | 9465 | 1.131 | 0.8173 | 1.565 | 0.4581 | Intergenic | SYT10;ALG10 |
| 12 | 3,36,95,992 | chr12:33695992:G:T | rs11052847 | T | 0.00689 | 0.99201 | Imputed | 6460 | 2.758 | 1.918 | 3.966 | 4.37E−08 | 9465 | 1.131 | 0.8173 | 1.565 | 0.4581 | Intergenic | SYT10;ALG10 |
| 12 | 13,29,15,197 | chr12:132915197:G:A | rs11147161 | A | 0.00503 | 0.96369 | Imputed | 6460 | 3.768 | 2.344 | 6.059 | 4.36E−08 | 9465 | 1.366 | 0.8825 | 2.115 | 0.1617 | Intergenic | LOC101928530;ZNF605 |
| 12 | 13,28,98,032 | chr12:132898032:A:C | rs12230138 | C | 0.00501 | 0.96567 | Imputed | 6460 | 3.899 | 2.436 | 6.239 | 1.41E−08 | 9465 | 1.411 | 0.9143 | 2.177 | 0.1199 | Intergenic | LOC101928530;ZNF605 |
| 15 | 6,97,78,062 | chr15:69778062:T:C | rs75516437 | C | 0.00621 | 0.64954 | Imputed | 6460 | 3.937 | 2.498 | 6.207 | 3.60E−09 | 9465 | 1.559 | 1.033 | 2.353 | 0.03452 | Intergenic | PCAT29;LINC00593 |
| 15 | 9,23,50,924 | chr15:92350924:T:C | T | 0.02086 | 0.30905 | Imputed | 6460 | 3.36 | 2.177 | 5.186 | 4.45E−08 | 9465 | 1.432 | 0.9822 | 2.089 | 0.06196 | Intergenic | SLCO3A1;ST8SIA2 | |
| 20 | 5,50,80,179 | chr20:55080179:G:A | rs144851111 | A | 0.00386 | 0.30246 | Imputed | 6460 | 8.283 | 4.084 | 16.8 | 4.62E−09 | 9465 | 2.649 | 1.352 | 5.191 | 0.00452 | Intergenic | DOK5;LINC01441 |
| 21 | 2,81,70,508 | chr21:28170508:A:C | rs2831598 | C | 0.00548 | 0.85895 | Imputed | 6460 | 3.812 | 2.421 | 6.001 | 7.48E−09 | 9465 | 1.972 | 1.34 | 2.903 | 0.000575 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,64,783 | chr21:28164783:C:T | rs139600098 | T | 0.00601 | 0.86242 | Imputed | 6460 | 3.641 | 2.37 | 5.594 | 3.69E−09 | 9465 | 1.825 | 1.265 | 2.631 | 0.001282 | ncRNA_intronic | LINC01695 |
| 21 | 2,84,29,678 | chr21:28429678:G:A | rs145901638 | A | 0.0053 | 0.8642 | Imputed | 6460 | 4.115 | 2.594 | 6.527 | 1.86E−09 | 9465 | 1.829 | 1.229 | 2.722 | 0.002898 | Intergenic | LINC01695;LINC00161 |
| 21 | 2,81,65,396 | chr21:28165396:C:A | rs140035545 | A | 0.00619 | 0.86512 | Imputed | 6460 | 3.714 | 2.449 | 5.631 | 6.48E−10 | 9465 | 1.887 | 1.322 | 2.694 | 0.000473 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,65,671 | chr21:28165671:C:G | rs2831578 | G | 0.0066 | 0.86537 | Imputed | 6460 | 3.54 | 2.359 | 5.312 | 1.04E−09 | 9465 | 1.789 | 1.265 | 2.531 | 0.001014 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,65,241 | chr21:28165241:T:A | rs138282731 | A | 0.00622 | 0.86591 | Imputed | 6460 | 3.714 | 2.449 | 5.631 | 6.48E−10 | 9465 | 1.887 | 1.322 | 2.694 | 0.000473 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,67,027 | chr21:28167027:G:A | rs2831584 | A | 0.006 | 0.87016 | Imputed | 6460 | 3.653 | 2.385 | 5.596 | 2.61E−09 | 9465 | 1.878 | 1.306 | 2.699 | 0.000666 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,68,119 | chr21:28168119:C:A | rs2831588 | A | 0.00661 | 0.8744 | Imputed | 6460 | 3.311 | 2.188 | 5.01 | 1.47E−08 | 9465 | 1.746 | 1.235 | 2.468 | 0.001598 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,70,454 | chr21:28170454:C:T | rs2831597 | T | 0.00518 | 0.88171 | Imputed | 6460 | 4.405 | 2.798 | 6.935 | 1.52E−10 | 9465 | 2.218 | 1.501 | 3.277 | 6.37E−05 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,71,717 | chr21:28171717:A:G | rs57177980 | G | 0.00563 | 0.88918 | Imputed | 6460 | 3.752 | 2.382 | 5.908 | 1.15E−08 | 9465 | 1.922 | 1.314 | 2.809 | 0.000749 | ncRNA_intronic | LINC01695 |
| 21 | 2,84,06,331 | chr21:28406331:T:C | rs150168760 | C | 0.0048 | 0.89787 | Imputed | 6460 | 4.157 | 2.613 | 6.614 | 1.80E−09 | 9465 | 1.735 | 1.151 | 2.614 | 0.00844 | Intergenic | LINC01695;LINC00161 |
| 21 | 2,81,87,913 | chr21:28187913:T:C | rs10482989 | C | 0.00602 | 0.93268 | Imputed | 6460 | 3.599 | 2.324 | 5.572 | 9.50E−09 | 9465 | 2.024 | 1.405 | 2.916 | 0.000155 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,89,835 | chr21:28189835:CT:C | C | 0.00604 | 0.93481 | Imputed | 6460 | 3.599 | 2.324 | 5.572 | 9.50E−09 | 9465 | 2.024 | 1.405 | 2.916 | 0.000155 | ncRNA_intronic | LINC01695 | |
| 21 | 2,81,99,184 | chr21:28199184:A:T | rs28883424 | T | 0.00564 | 0.9351 | Imputed | 6460 | 3.761 | 2.405 | 5.881 | 6.35E−09 | 9465 | 2.012 | 1.384 | 2.925 | 0.000252 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,90,781 | chr21:28190781:TAC:T | T | 0.00502 | 0.93737 | Imputed | 6460 | 4 | 2.524 | 6.338 | 3.58E−09 | 9465 | 1.999 | 1.354 | 2.951 | 0.000494 | ncRNA_intronic | LINC01695 | |
| 21 | 2,81,99,308 | chr21:28199308:A:G | rs8130449 | G | 0.00605 | 0.9382 | Imputed | 6460 | 3.599 | 2.324 | 5.572 | 9.50E−09 | 9465 | 2.024 | 1.405 | 2.916 | 0.000155 | ncRNA_intronic | LINC01695 |
| 21 | 2,81,97,976 | chr21:28197976:C:T | rs59067393 | T | 0.00502 | 0.93881 | Imputed | 6460 | 4 | 2.524 | 6.338 | 3.58E−09 | 9465 | 1.999 | 1.354 | 2.951 | 0.000494 | ncRNA_intronic | LINC01695 |
| 21 | 2,82,03,693 | chr21:28203693:G:A | rs78202304 | A | 0.00578 | 0.95837 | Imputed | 6460 | 3.82 | 2.454 | 5.948 | 2.97E−09 | 9465 | 2.141 | 1.478 | 3.101 | 5.69E−05 | ncRNA_intronic | LINC01695 |
| 21 | 2,82,25,654 | chr21:28225654:C:T | rs73897628 | T | 0.00536 | 0.96681 | Imputed | 6460 | 3.635 | 2.309 | 5.721 | 2.45E−08 | 9465 | 1.739 | 1.185 | 2.551 | 0.004699 | ncRNA_intronic | LINC01695 |
| 21 | 2,83,52,351 | chr21:28352351:G:T | rs7278151 | T | 0.00874 | 0.96719 | Imputed | 6460 | 2.909 | 2.029 | 4.172 | 6.37E−09 | 9465 | 1.379 | 1.015 | 1.873 | 0.04014 | Intergenic | LINC01695;LINC00161 |
| 21 | 2,82,06,978 | chr21:28206978:G:A | rs144947925 | A | 0.00515 | 0.97068 | Imputed | 6460 | 3.938 | 2.507 | 6.185 | 2.66E−09 | 9465 | 1.939 | 1.323 | 2.842 | 0.000692 | ncRNA_intronic | LINC01695 |
| 21 | 2,82,06,642 | chr21:28206642:G:C | rs16997642 | C | 0.00558 | 0.97287 | Imputed | 6460 | 3.866 | 2.484 | 6.019 | 2.12E−09 | 9465 | 2.031 | 1.4 | 2.946 | 0.000189 | ncRNA_intronic | LINC01695 |
| 21 | 2,82,22,390 | chr21:28222390:T:C | rs2831662 | C | 0.00587 | 0.97928 | Imputed | 6460 | 3.606 | 2.318 | 5.611 | 1.30E−08 | 9465 | 1.725 | 1.193 | 2.496 | 0.003782 | ncRNA_intronic | LINC01695 |
| 21 | 2,83,36,083 | chr21:28336083:T:C | rs73897689 | C | 0.00493 | 0.98436 | Imputed | 6460 | 3.822 | 2.406 | 6.072 | 1.38E−08 | 9465 | 1.792 | 1.208 | 2.658 | 0.003747 | Intergenic | LINC01695;LINC00161 |
| 21 | 2,83,37,534 | chr21:28337534:T:C | rs73897690 | C | 0.00489 | 0.98684 | Imputed | 6460 | 3.822 | 2.406 | 6.072 | 1.38E−08 | 9465 | 1.807 | 1.217 | 2.683 | 0.003374 | Intergenic | LINC01695;LINC00161 |
| 21 | 3,45,50,989 | chr21:34550989:C:T | rs140276394 | T | 0.0032 | 0.50721 | Imputed | 6460 | 6.028 | 3.245 | 11.2 | 1.31E−08 | 9465 | 1.888 | 1.025 | 3.478 | 0.04147 | Intronic | RCAN1 |