Fig. 6.

Fits of the model calibrated by C1-3 and C1 to the empirical data of study 1. Bars indicate the average of the best 100 simulations (S-) and the corresponding empirical data (E-) for increasing Mg²⁺ ion concentrations. The error bars on the empirical data shows the standard deviations. The error bars on the simulation results indicate the standard deviation of the 100 best fits. Stars indicate the statistically significant differences between values given for the empirical data compared to the control (Mg²⁺ concentration of 0.8 mM) (p < 0.05 = *; p < 0.01 = **; p < 0.001 = ***). $\stackrel{-}{R^2}$ is the average $R^2$ calculated for each measurement item.