Fig. 5. Spearman rank correlation analysis between the fold-change in receptor binding and the associated fold-change in RNA expression under stress and circadian conditions.

The results of the correlation analysis are depicted in the subfigures. A significant positive correlation was found between the fold-change in MR binding and the fold-change in inRNA levels after exposure to acute stress (a) and during the circadian rise (b). The change in GR binding post-stress did not significantly correlate with the change in inRNA levels (c). The increased GR binding and the changes in inRNA levels as a result of the circadian rise, however, showed a significant positive correlation (d). Source data are provided in the Source Data File.