Table 1. Characteristics and rates of infants receiving a diagnosis of neonatal abstinence syndrome vs. all other US hospital births, 2018.
LOS: length of stay; NAS: neonatal abstinence syndrome; CI: confidence interval
| NAS rate per 1000 births | NAS n = %, (95% CI) | All other newborn hospitalizations n = %, (95% CI) | P-value | |
| Overall | 7.1 (6.8-7.3) | |||
| Sex | 0.02 | |||
| Male | 7.4 (7.1-7.6) | 52.9 (51.7-54.2) | 51.0 (50.9-51.1) | |
| Female | 6.8 (6.6-7.0) | 47.0 (45.7-48.3) | 49.0 (48.8-49.1) | |
| Race/ Ethnicity | < .0001> | |||
| White | 10.7 (10.3-11.0) | 69.8 (67.7-71.9) | 46.2 (44.9-47.4) | |
| Black | 4.1 (3.7-4.4) | 7.7 (6.7-8.7) | 13.4 (12.7-14.1) | |
| Hispanic | 2.8 (2.5-3.0) | 7.2 (6.1-8.2) | 18.5 (17.4-19.5) | |
| Native American/ Alaska native | 0.5 (0.3-0.8) | 0.4 (0.2-0.6) | 5.4 (4.9-5.9) | |
| Other | 5.2 (4.5-5.8) | 5.4 (4.3-6.5) | 7.4 (6.8-7.9) | |
| Household income, quartile | < .0001> | |||
| 1st | 9.5 (9.0-9.5) | 35.9 (33.6-38.2) | 26.8 (25.7-27.9) | |
| 2nd | 8.2 (7.9-8.6) | 30.0 (28.3-31.7) | 25.7 (24.9-26.5) | |
| 3rd | 6.2 (5.9-6.5) | 21.5 (20.0-23.1) | 24.5 (23.8-25.2) | |
| 4th | 3.7 (3.5-3.8) | 11.4 (10.2-12.6) | 22.1 (20.8-23.4) | |
| Payment | < .0001> | |||
| Medicaid | 13.2 (12.8-13.6) | 84.1 (82.8-85.3) | 44.7 (43.6-45.9) | |
| Private | 1.5 (1.4-1.6) | 10.0 (9.0-11.0) | 47.1 (45.9-48.3) | |
| Uninsured | 6.2 (5.6-6.6) | 4.4 (3.7-5.1) | 5.1 (4.7-5.5) | |
| Other | 3.3 (2.7-3.8) | 1.3 (1.0-1.7) | 2.9 (2.7-3.1) | |
| Hospital bed-size | 0.05 | |||
| Small | 6.8 (6.5-7.1) | 18.7 (16.7-20.6) | 19.5 (18.3-20.7) | |
| Medium | 6.4 (6.0-6.7) | 27.6 (25.1-30.2) | 30.6 (29.2-31.9) | |
| Large | 7.6 (7.3-7.9) | 53.7 (50.8-56.6) | 49.9 (48.4-51.5) | |
| Urban/ Rural | < .0001> | |||
| Rural | 10.5 (9.1-11.7) | 13.2 (11.1-15.2) | 9.0 (8.5-9.4) | |
| Urban non-Teaching | 6.2 (5.8-6.5) | 16.8 (14.9-18.6) | 19.4 (18.4-20.5) | |
| Urban teaching | 7.0 (6.7-7.2) | 70.1 (67.5-72.6) | 71.6 (70.4-72.7) | |
| Delivery hospital region | < .0001> | |||
| Northeast | 9.4 (8.9-9.9) | 21.0 (18.6-23.5) | 15.7 (14.6-16.9) | |
| Midwest | 6.6 (6.1-7.0) | 19.7 (17.5-21.9) | 21.3 (20.1-22.4) | |
| South | 7.6 (7.2-7.9) | 42.2 (39.3-45.2) | 39.5 (37.9-41.0) | |
| West | 5.1 (4.8-5.4) | 17.1 (15.2-18.9) | 23.5 (22.3-24.8) |