REAGENT or RESOURCE	SOURCE	IDENTIFIER
Chemicals, peptides, and recombinant proteins
Dexamethasone	Sigma	Cat#D4902-25MG
DMSO	VWR	Cat#472301-100ML
Hyperova	Cosmo Bio	Cat#KYD-010-EX-X5
KSOM	Millipore	Cat#MR-121-D
Trizol	Thermo Scientific	Cat#15596026
Directzol	Zymo	Cat#R2080
M-MLV	Promega	Cat#M1701
Recombinant RNAsin Ribonuclease inhibitor	Promega	Cat#N2111
Insulin	Novo Nordisk	Cat#Actrapid
Critical commercial assays
exoRNeasy Serum/Plasma Midi Kit	Qiagen	Cat#77044
Truseq small RNA library kit	Ilumina	Cat#RS-200-0012
Truseq Total RNA library kit	Ilumina	Cat#RS-122-2301
Nextflex small RNA library kit	Perkin Elmer	Cat#NOVA-5132-05
Nextera XT DNA Library Preparation Kit	Ilumina	Cat#FC-131-1024
miRCURY LNA RT Kit	Qiagen	Cat#339340
miRCURY® LNA® miRNA SYBR® Green PCR	Qiagen	Cat#339345
Deposited data
Sperm small and long RNA sequencing data	Gene Omnibus	GSE162112
2-cell embryo RNA sequencing data	ENA	ERP105660
Experimental models: Organisms/strains
C57Bl/6Jrj mice	Janvier lab
C57Bl/6 CBLT mice	Sanger Institute
Oligonucleotides
mirCURY LNA miRNA PCR Assay ArgCCT-2 5`GCCCCAGUGGCCUAAUGGAUAAGGCACUGGCC3`	Qiagen	Cat#339317
mirCURY LNA miRNA PCR Assay Gly-GCC-2 5`GCAUUGGUGGUUCAGUGGUAGAAUUCUCGCCU3`	Qiagen	Cat#339317
mirCURY LNA miRNA PCR Assay His-GTG-3 5`GCCGUGAUCGUAUAGUGGUUAGUACUCUGCGU3`	Qiagen	Cat#339317
mirCURY LNA miRNA PCR Assay Leu-CAA-2 5`GUCAGGAUGGCCGAGUGGUCUAAGGCGCCAGA3`	Qiagen	Cat#339317
mirCURY LNA miRNA PCR Assay RnU6	Qiagen	Cat#339317
mmu-miR-677-p5 mirCURY LNA miRNA PCR Assay	Qiagen	Cat#339306
mmu-miR-3535 mirCURY LNA miRNA PCR Assay	Qiagen	Cat#339306
mmu-miR-6538 mirCURY LNA miRNA PCR Assay	Qiagen	Cat#339306
CircTasp1 FW `CTT AGG AGA GAT TGA ATG TGA TGC C` RW `AAA GGG AGT CAA CCA CTC AG`	Microsynth	Cat#4059186 & 4059187
CircDennd1 FW `AGCTTTCCCAGTTTATTGATGGT` RW `GAAGCCACCCGAAGTGATCT`	Microsynth	Cat#4059182 & 4059183
Software and algorithms
Code	Github	https://github.com/ETHZ-INS/Sperm-RNA-Dex).
GraphPad Prism	GraphPad Prism version 8	www.graphpad.com
featureCounts	Liao et al. (2014)	http://subread.sourceforge.net/
DESeq2	Love et al. (2014)	https://bioconductor.org/packages/release/bioc/html/DESeq2.html
edgeR	Anders et al. (2013)	https://bioconductor.org/packages/release/bioc/html/edgeR.html
STAR	Dobin et al. (2013)	https://github.com/alexdobin/STAR
CIRCexplorer2	Zhang et al. (2016)	https://circexplorer2.readthedocs.io
Scater	McCarthy et al. (2017)	https://bioconductor.org/packages/release/bioc/html/scater.html
Monocle	Qiu et al. (2017)	http://cole-trapnell-lab.github.io/monocle-release/
Trimmomatic	Bolger et al. (2014)	www.usadellab.org
Cutadapt	Martin (2011)	https://cutadapt.readthedocs.io