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. 2021 May 7;12(3):1001–1019. doi: 10.1016/j.jcmgh.2021.04.013

Figure 4.

Figure 4

GSK672 and FGF15 combined treatment decreases adiposity and adipose inflammation in the 32-week HFCFr diet-fed mice. Mice and experiments are described as in Figure 3A. (A) Gonadal fat weight. (B) Representative H&E staining of white adipose tissue. Scale bar = 250 μm. (C) Average adipocyte diameter is calculated with ImageJ software. About 160–360 cells/mouse are measured. (D) Representative F4/80 immunohistochemical staining. Scale bar = 250 μm. (E) F4/80 positive area per field is quantified with ImageJ software. Mean value of HFCFr group is set as “1”. Results are mean ± SEM. One-way ANOVA and Tukey post hoc were used to calculate the P value for A, C, and E. ∗ vs HFCFr diet. (n = 6–7).