Table 3.

Genes Representing Altered Integrin Signaling Pathway Generated By Ingenuity Pathway Analysis

	HFCFr/Chow	HFCFr + GSK/HFCFr	HFCFr + FGF15/HFCFr	HFCFr + FGF15 + GSK/HFCFr
Gene symbol	Expr fold change	Expr fold change	Expr fold change	Expr fold change
ACTA2	3.43			–3.75
ACTB	2.2		–1.73	–2.4
ACTN1	4.07	–1.28	–1.33	–1.98
ACTN4	1.9		–1.42	–1.48
ACTR2	2.12		–1.27	–1.52
ACTR3	2.21	–1.24	–1.43	–2.31
AKT1	1.69	–1.39	–1.27	–1.53
ARF1	1.41	–1.2	–1.48	–1.63
ARF4	1.27			–1.22
ARHGAP5	–1.33
ARPC1B	2.35	–1.49	–1.42	–2.04
ARPC2	1.42	–1.22	–1.25	–1.39
ARPC4	1.38			–1.42
ARPC5	1.52	–1.2	–1.33	–1.42
CAPNS1	2.23		–1.35	–1.56
Cdc42	2.4		–1.3	–1.69
FYN	2.79
GRB2	1.57		–1.31	–1.43
HRAS	1.54		–1.56
ILKAP	1.23
ITGB1	1.34			–1.27
ITGB2	6.87
MAP2K2	–1.2
MAP2K4			–1.49
MYL12A	2.42		–1.61	–1.94
MYL12B	4.36		–1.54	–2.28
NCK1			–1.32	–1.22
PAK2			–1.69
PIK3R1	1.92			–1.43
RAC1	1.82		–1.22	–1.48
RAC2	5.77
RALA	1.76
RALB	3.34
RAP1A	1.72			–1.22
RAP1B	1.53		–1.25	–1.44
RHOG	2.1			–1.6
RND3	2.03			–1.58
TLN1	1.81
VASP	4.34	–1.73	–1.84	–2.41
Wasl	1.68
WIPF1	7.44