Fig. 2.

Composite eFBB SUVR, R1, and dFBB SUVR in the groups. Comparison of the eFBB SUVR, R1, and dFBB SUVR of the composite cortical regions according to three diagnostic groups. Both the eFBB (A) and R1 (B) images showed significant perfusion reductions in the Aβ⁺AD group compared with the Aβ⁻NC and Aβ⁺MCI groups. The composite dFBB SUVR (C) showed significant Aβ depositions in the Aβ⁺MCI and Aβ⁺AD groups compared with the Aβ⁻NC group (*; p < 0.05/7). Abbreviations: Aβ⁻NC, Aβ-negative normal cognition; Aβ⁺MCI, Aβ-positive mild cognitive impairment; Aβ⁺AD, Aβ-positive Alzheimer’s disease with dementia