Statistical parametric maps from eFBB images. Statistical parametric maps of the hypoperfusion patterns obtained from eFBB (0–10 min) images in the Aβ+MCI group compared with the Aβ−NC group (A: uncorrected p < 0.001, t > 3.31) and in the Aβ+AD group compared with the Aβ+MCI group (B: FDR-corrected p < 0.05, t > 2.41). Abbreviations: Aβ−NC, Aβ-negative normal cognition; Aβ+MCI, Aβ-positive mild cognitive impairment; Aβ+AD, Aβ-positive Alzheimer’s disease with dementia