Table 1.

List of potential Prdx2 interactors from BioID after data filtering for upregulated Prdx2 interactome with indication of accession, description, and values in abundance ratio: (auranofin treatment)/(negative control); abundance ratio: (xanthine/xanthine oxidase treatment)/(negative control); abundance ratio: (auranofin treatment)/(PBS treatment) and abundance ratio: (xanthine/xanthine oxidase treatment)/(PBS treatment). And additional information of numbers of cysteine residues and cited sulphenylation sites.

UniProt Accession	Description and Gene name	Abundance Ratio: (auranofin treatment)/(negative control)	Abundance Ratio: (xanthine/xanthine oxidase treatment)/(negative control)	Abundance Ratio: (auranofin treatment)/(PBS treatment)	Abundance Ratio: (xanthine/xanthine oxidase treatment)/(PBS treatment)	Numbers of Cysteine residues	Sulphenylation sites
P07437a	Tubulin beta chain TUBB	100	100	100	100	8
P50395a	Rab GDP dissociation inhibitor GDI2	100	100	100	100	8	C277, C302 [62]
Q8WUM0a	Nuclear pore complex protein Nup133 NUP133	100	100	100	100	18
P26196	Probable ATP-dependent RNA helicase DDX6 DDX6	100		100		7	C102 [62]
P52756a	RNA-binding protein 5 RBM5	100	100	100	100	9
Q01968a	Inositol polyphosphate 5-phosphatase OCRL-1 OCRL	100	100	100	100	21
Q9NTJ3	Structural maintenance of chromosomes protein 4 SMC4	100		100	0.01	12	C916 [62]
Q92905a	COP9 signalosome complex subunit 5 JAB1/CSN5/COPS5	100	100	9.446	13.886	4	C218 [62]
P68133	Actin, alpha skeletal muscle ACTA1	19.794	100	1	100	6
Q15393	Splicing factor 3B subunit 3 SF3B3	15.795	100	8.318	100	19	C269, C1054, C1156 [62]
P61011	Signal recognition particle 54 kDa protein SRP54	0.755	100	1	100	5
Q9Y224	RNA transcription, translation and transport factor protein C14orf166		100	0.01	100	2
O75694	Nuclear pore complex protein Nup155 NUP155	1	100	0.869	100	28

^aSix potential Prdx2 interactor candidates marked with an asterisk are upregulated in both H₂O₂ elevating conditions.