Table 2.

List of potential Prdx2 interactors from DSP-IP after data filtering for upregulated Prdx2 interactome with indication of accession, description, and values in abundance ratio: (auranofin treatment)/(negative control); abundance ratio: (xanthine/xanthine oxidase treatment)/(negative control); abundance ratio: (auranofin treatment)/(PBS treatment) and abundance ratio: (xanthine/xanthine oxidase treatment)/(PBS treatment).

UniProt Accession	Description and Gene name	Abundance Ratio: (auranofin treatment)/(negative control)	Abundance Ratio: (xanthine/xanthine oxidase treatment)/(negative control)	Abundance Ratio: (auranofin treatment)/(PBS treatment)	Abundance Ratio: (xanthine/xanthine oxidase treatment)/(PBS treatment)
Q13813-3a	Isoform 3 of Spectrin alpha chain, non-erythrocytic 1 SPTAN1	100	100	2.063	100
H3BSK9	Ataxin-2-like protein (Fragment) ATXN2L	100	0.01	100	0.01
Q562R1a	Beta-actin-like protein 2 ACTBL2	100	100	3.384	100
K7EJH8a	Alpha-actinin-4 (Fragment) ACTN4	100	100	2.602	2.855
O43818a	U3 small nucleolar RNA-interacting protein 2 RRP9	100	100	2.36	6.889
Q9BPX5	Actin-related protein 2/3 complex subunit 5-like protein ARPC5L	100	100	1.779	1.553
F8WBT5a	PIN2/TERF1-interacting telomerase inhibitor 1 PINX1	100	100	100	100
Q9NVP1a	ATP-dependent RNA helicase DDX18 DDX18	100	100	100	100
P55769	NHP2-like protein 1 NHP2L1	100	1	100	3.302
C9JH19	Cathepsin D light chain (Fragment) CTSD	100	100	100	1
O15042	U2 snRNP-associated SURP motif-containing protein U2SURP		100		100
P31944	Caspase-14 CASP14		100	0.01	3.616
F8VS07	LIM domain and actin-binding protein 1 LIMA1	100	100		2.921
P04083	Annexin A1 ANXA1		100		100
P06396	Gelsolin GSN	100	100		100
Q9NZR1	Tropomodulin-2 TMOD2		100		100
Q9NP55	BPI fold-containing family A member 1 BPIFA1		100		100
Q53RT3	Retroviral-like aspartic protease 1 ASPRV1		100		100
Q08188	Protein-glutamine gamma-glutamyltransferase E TGM3	0.01	100		100

^aSix potential Prdx2 interactor candidates marked with an asterisk are upregulated in both H₂O₂ elevating conditions.