Table 2.
Minimal biofilm eradication concentration (MBEC) for vancomycin against biofilms or suspended aggregates of S. epidermidis expressing PIA or Embp. Biofilms were formed by induction of PIA production in S. epidermidis 1585pTXicaADBC or Embp production in S. epidermidis 1585Pxyl/tetembp in either BHI or BHI with 10 % (v/v) human plasma (BHI+HP).
|
S. epidermidis 1585 strain: |
Aggregates (BHI) |
Aggregates (BHI+HP) |
Biofilm in wells (BHI) |
Biofilm in wells (BHI+HP) |
|---|---|---|---|---|
|
pTXicaADBC |
>2048 mg l−1 |
>2048 mg l−1 |
>2048 mg l−1 |
>2048 mg l−1 |
|
Pxyl/tet embp |
>2048 mg l−1 |
>2048 mg l−1 |
>2048 mg l−1 |
>2048 mg l−1 |