Table 3.

FICI values for the two-drug and three-drug combinations of furazolidone, vancomycin and sodium deoxycholate

	FICI
Strain	FZ+DOC	FZ+Van	DOC+Van	FZ+Van+DOC
E. coli ATCC 25922	0.16	0.75	0.52	0.11
E. coli K1508	<0.50	0.75	<1.02	<0.13
E. coli ERL034336	0.27	0.50	1.01	0.30
E. coli UPEC P191	0.19	0.75	0.28	0.17
E. coli NZRM 4364	<0.31*	0.9	<0.52*	<0.35*
E. coli NZRM 4402	0.19	0.74	0.23	0.19
E. coli NZRM 4457	<0.75*	<1*	1	<0.54*
E. coli NZRM 4524	0.19	0.35	0.53	0.17
C. gillenii PMR001	0.17	0.5	1	0.27
K. pneumoniae PMR001	1	0.53	1	0.51
K. pneumoniae NZRM 4387	0.31	0.63	1	0.28
K.pneumoniae NZRM 4412	1	1	0.53	0.54
K. pneumoniae NZRM 4498	<0.52*	0.38	<1*	<0.26*
Salmonella enterica sv. Typhimurium LT2	0.31	0.56	1	0.53
Salmonella enterica NZRM4533	0.38	0.5	1	0.27
Shigella dysenteriae NZRM 1015	<0.25*	0.5	<0.52*	<0.28*
A. lwoffi NZRM 1218	0.25	0.82	0.46	0.29
A. baumannii NZRM 3697	0.28	0.75	1	0.32
A. baumannii NZRM 4408	<0.09*	0.56	1	<0.13*
P. dagmatis NZRM 959	0.75	0.75	0.63	0.66

FZ, furazolidone; DOC, sodium deoxycholate; Van, vancomycin.

*MIC is higher than the highest tested concentration which was used to calculate the FICI, and therefore the actual FICI is lower than the calculated value; values in bold indicate synergy (FICI≤0.5).