Table 2.

Interactions and total stabilizing energy in the most dynamic-stable conformation

Items	SARS	SARS-CoV-2	HP5	LL37
H-bond number	12 (19)	12 (19)	9 (13)	9 (15)
Salt bridges	4	2	1	2
Electrostatic interactions	5 (1)	3 (1)	5 (4)	9 (6)
Hydrophobic interactions	1	1	3	7
van der Waals pairs	8344	8629	6681	10,365
Interface residues	87	93	53	82
H-bond energy (kJ/mol)	− 75.20	− 80.31	− 64.10	− 69.87
Electrostatic energy (kJ/mol)	20.86	− 8.90	− 17.16	− 25.35
VdW energy (kJ/mol)	− 243.42	− 238.42	− 182.81	− 252.36
Stabilizing energy (kJ/mol)	− 297.76	− 327.63	− 264.07	− 347.58

PPCheck server [34] only processes a single conformation. Therefore, no error was encountered in the above data. The number of H-bonds enclosed in brackets means the highest H-bond number that could be formed. Similarly, the electrostatic interactions in brackets suggest the amount of unfavorable electrostatic linkages