UGP2 and YAP regulate glycogen metabolism in PDAC cells. (A) UDP-glucose levels of Panc1, MiaPaca2, and Suit2 cells with shYAP or empty vector. *P < 0.05 by ANOVA; n.s., not significant. (B) Cellular glycogen levels in Panc1, MiaPaca2, or Suit2 cells with shYAP or empty vector control. **P < 0.01, ***P < 0.001. Error bars represent SEM. (C) Relative viability of Panc1 cells with vector control or shUGP2 grown with or without 100 μM UDP-glucose for 7 d. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.