Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 28;22(15):8109. doi: 10.3390/ijms22158109

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Model of prostate epithelial stem cell hierarchy based upon keratin profiles. Quiescent prostate stem cells (cluster I: enriched for KRT13, 23, 80, 78, 4) become active stem cells (cluster II), with increased expression of KRT 16, 17, and 6 that generate bipotent progenitor cells (cluster III) and further give rise to committed unique potent basal progenitors (cluster IV: enriched for KRT5, 14, 6, 16), as well as early (cluster V) and late-stage (cluster VI) luminal progenitors (enriched for KRT8, 18, 10).