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. 2021 Jul 31;22(15):8285. doi: 10.3390/ijms22158285

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The closed relationship between small interfering RNA (siRNA) expression and DNA methylation. The distribution of siRNA expression (A) and length (B) among varying classes of TEs. (C) The expression level of siRNA in genes and TEs. (D) The correlation of siRNA expression (x-axis) and DNA methylation level (y-axis) in different regions. The green lines fit the regression between siRNA abundance and DNA methylation level by genear linear model. (E) The proportion of up-/down-regulated siRNA in hyper-DMRs or hypo-DMRs under WS. ***: p < 0.001, χ² test.