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. 2021 Jul 30;13(15):2529. doi: 10.3390/polym13152529

Table 1.

Structural Classification of Liposomes Based on Size and Number of Lamellae.

Lamellarity Abbreviation Number of Lipid Bilayers Diameter Size Rang Structures
(1) Unilamellar Vesicles ULV one lipid bilayer All size range graphic file with name polymers-13-02529-i001.jpg
Dimensions
Name Abbreviation Size Range (µm) Characteristics
 Single Unilamellar Vesicles  SUV  0.02–0.20  useful for entrapping lipophilic active materials
 Medium Unilamellar Vesicles  MUV  0.20–0.50  slightly more efficient than SUV
 Large Unilamellar Vesicles  LUV  0.50–10  capable of capturing a significant amount of hydrophilic material
 Giant Unilamellar Vesicles  GUV  100–200  look like cell membranes, ideal templates for microscale bioreactors
(2) Oligolamellar Vesicles OLV few concentric lipid bilayers 100–500 nm graphic file with name polymers-13-02529-i002.jpg
(3) Multilamellar Vesicles MLV many concentric lipid bilayers >500 nm graphic file with name polymers-13-02529-i003.jpg
(4) Multivesicular Vesicles MVV non-concentric vesicles within a single lipid bilayer >1000 nm graphic file with name polymers-13-02529-i004.jpg