Table 1.
Commercially available cosmetics incorporating HA and HA derivatives.
| Cosmetic Product Category/Proposed Use | Producer (Country of Origin)/Cosmetic Product Trade Name | HA Form | Other Active Ingredients Incorporated in the Cosmetic Formulation (INCI—International Nomenclature of Cosmetic Ingredients Denomination) | Cosmetic Claim | Market Segment | Reference |
|---|---|---|---|---|---|---|
| Skin care cosmetics | FRESH (USA) Deep Hydration Face Serum Serum |
NaHA | Porphyridium Cruentum Extract, Pyrus Cydonia Seed Extract, Angelica Keiskei Extract, Voandzeia Subterra Nea Seed Extract, Cucumis Sativus (Cucumber) Fruit Extract, Tocopheryl Acetate | 24-h moisture | Premium Market | [108] |
| DECIEM (Canada) The ORDINARY “Buffet” Multi-Technology Peptide Serum Serum |
NaHA | Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl BenzylamideDiacetate, Acetylarginyltryptophyl Diphenylglycine, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanin, Arginine, Aspartic, Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Hydroxypropyl Cyclodextrin |
anti-ageing | Premium Market | [109] | |
| DECIEM (Canada) THE ORDINARY Hyaluronic Acid 2% + B5 Serum |
NaHA | Panthenol, Ahnfeltia Concinna Extract | moisturizing, anti-ageing |
Premium Market | [110] | |
| APIVITA (Greece) 5-action Eye Serum Advanced eye care Serum |
Hydrolyzed HA | Lilium Candidum Extract, PfaffiaPaniculata Extract, PtychopetalumOlacoides Extract, CopperLysinate/Prolinate, Propolis Extract, Mel Extract, Methylglucoside Phosphate, Euphrasia Officinalis Extract, Lecithin, Hydroxypropyl Cyclodextrin, Ascorbyl Tetraisopalmitate, Panthenol, SideritisPerfoliata Extract, Aloe Barbadensis Extract, SideritisScardica Extract, SideritisRaeseri Extract, Bisabolol | anti-ageing, moisturizing | Premium Market | [111] | |
| FARMEC (Romania) Hyaluronic Acid ampoules 5% Serum |
NaHA | Superoxide Dismutase, Lecithin | anti-wrinkle, intensive moisturizing |
Mass Market | [112] | |
| AVIVA COSMETICS (Romania) INFINITUM Deep Wrinkles Anti-Ageing Serum |
Hydrolyzed HA | Aesculus Hippocastanum Extract | firming, anti-ageing | Premium Market | [113] | |
| GARANCIA (France) MYSTÉRIEUX MILLE ET UN JOURS Anti-Ageing Day Emulsion | Hydrolyzed HA | Alaria Esculenta Extract, Cyathea Cumingii Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38 | relax expression lines | Premium Market | [114] | |
| BALANCE ME (UK) Tinted Wonder Eye Cream Eye cream complexion perfection Day Cream |
Hydrolyzed HA | Picea Abies Extract, Rubus Chamaemorus Seed Extract, Aloe Barbadensis Extract, Styrax Benzoin Extract, Rosmarinus Officinalis Extract, Vitis Vinifera Seed Extract, Tocopherol | soothing, anti-ageing |
Mass Market | [115] | |
| EARTH SCIENCE (USA) Apricot Intensive night cream Night Cream |
NaHA | Pyrus Malus Extract, Glycyrrhiza Glabra Extract, Glycine Soja Seed Extract, Tocopherol, Citrus Grandis Seed Extract, Calendula Officinalis Extract, Bambusa Arundinacea Extract, Sambucus Nigra Extract, Cucumis Sativus Extract, Arnica Montana Extract, Hedera Helix Extract, Lactic acid, Allantoin | reduces the appearance of fine lines and wrinkles | Mass Market | [116] | |
| COSMETIC PLANT (Romania) Lift Up—Hyaluronic Acid Day Anti-Ageing Cream Day Cream |
Hydrolyzed HA | Porphyridium Cruentum Extract, Magnolia Liliflora Extract, Tocopherol | anti-ageing | Mass Market | [117] | |
| AVIVA COSMETICS (Romania) INFINITUM Cellular Regenerating Cream |
Hydrolyzed HA | Aesculus Hippocastanum Extract, Tocopheryl Acetate | firming, regenerating, rejuvenating | Premium Market | [118] | |
| GEROCOSSEN (Romania) Hyaluron Anti-Age CreamSPF 10 Day Cream |
NaHA | Lecithin, Tocopheryl acetate, Retinyl palmitate | anti-ageing | Mass Market | [119] | |
| AVIVA COSMETICS (Romania) INFINITUM Golden Elixir Anti-Ageing Cream SPF 15 Day Cream |
Hydrolyzed HA | Aesculus Hippocastanum Extract, Gold (CI 777480), Ectoin | firming, anti-ageing, SPF 15 |
Premium Market | [120] | |
| FARMEC (Romania) Anti-Wrinkle Cream Concentrated with Hyaluronic Acid 3% Day Cream |
NaHA | Pseudoalteromonas Ferment Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Tripeptide-1, Lecithin, Artemia Salina Extract, Superoxide Dismutase | anti-wrinkle, line filling and smoothing, intense hydration | Mass Market | [121] | |
| ARBONNE RE9 (USA) Advanced For Men Anti-Aging Moisturizer Broad Spectrum Men Care |
NaHA | Aloe Barbadensis Gel, Ceratonia Siliqua Extract, Laminaria Digitata Extract, Malachite Extract, Chamomilla Recutita Extract, Sophora Japonica Flower Extract, Tripleurospermum Maritimum Extract | moisturizing, SPF 15 | Premium Market | [122] | |
| AVIVA COSMETICS (Romania) INFINITUM Anti-Ageing Cleansing Emulsion |
Hydrolyzed HA | Aesculus Hippocastanum Extract | firming, anti-ageing |
Premium Market | [123] | |
| JONZAC (France) Bébé Bio Dermo-Repair Cream Baby Care |
Hydrolyzed HA | Malva Sylvestris Extract, Tocopherol, Hydrogenated Lecithin | soothing, regenerating, protecting | Mass Market | [124] | |
| Body cosmetics | LES MERVEILLEUSES LADUREE (France) Sun Protection Body Cream Body Cream |
NaHA | Rosa Centifolia Extract, Rosa Damascena Extract | hydrating, SPF 50 |
Premium Market | [125] |
| NATURE REPUBLIC (South Korea) Ice Sun, Ice Puff Sun Sun/Sunbed Exposure |
NaHA | Calendula Officinalis Extract | anti-wrinkle and skin bleftening, SPF 50 | Mass Market | [126] | |
| DM ALVERDE NATURKOSMETIK (Germany) Ivital + Hand cream |
NaHA | Amaranthus Caudatus Extract, Triticum Aestivum Germ Extract, Punica Granatum Extract, Tocopherol | smoothes lines and wrinkles | Mass Market | [127] | |
| INNISFREE (South Korea) My Body Tangerine Blossom Body lotion |
Hydrolyzed HA | Citrus Unshiu Peel Extract, Algae Extract, Eclipta Prostrata Extract, Orhid Extract, Camelia Sinensis Extract, Camelia Japonica Extract, Opuntia Coccinellifera Extract, Tocopherys Acetate | moisturizing | Mass Market | [128] | |
| INNISFREE (South Korea) Wine Peeling Jelly Scrub Peeling Scrub |
NaHA | Vitis ViniferaExtract, Ulmus Davidiana Root Extract, Amaranthus Caudatus Extract, Centella Asiatica Extract, Ficus Carica Extract, Citrus Unshiu Extract, Orchis Extract, Camelia Sinensis Extract, Camelia Japonica Extract, Opuntia Coccinellifera Extract, Niacinamide, Allantoin, Ceramide 3 | moisturizing | Mass Market | [129] | |
| TUDE HOUSE (South Korea) Berry AHA! Bleft Peel Bubble Wash |
Hydrolyzed HA | Algae Extract, Eclipta Prostrata Extract, Vaccinium Myrtillus Extract, Saccharum Officinarum Extract, Citrus Limonum Extract, Citrus Aurantium Dulcis Extract, Ulmus Davidiana Extract, Amaranthus Caudatus Extract, Acer Saccharinum Extract, Nymphaea Alba Extract, Bifida Ferment Lysate, Lecitin | bleftening | Mass Market | [130] | |
| Makeup cosmetics | ILLAMASQUA (UK) HYPNOTICA Lipe Lure Colour intense Liquid lipstick |
NaHA | N | long-wearing, picture-perfect finish | Premium Market | [131] |
| CLINIQUE (USA) Sun-Kissed Face Gelee Complexion multitasker |
NaHA | N | moisturizing | Premium Market | [132] | |
| PAUL& JOE (Japan) Pore SmoothingPrimer Face primer |
Hydrolyzed HA | Calendula Officianlis Extract, Rosa Canina Fruit Extract, Tocopherol | moisturizing | Premium Market | [133] |
NaHA—Sodium Hyaluronate; Hydrolized HA—Hydrolized Hyaluronic Acid; N—Not known.