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. 2021 Jul 28;22(15):8090. doi: 10.3390/ijms22158090

Table 5.

CredibleMeds® list of drugs with a conditional risk for TdP and risk factors.

Drug Increased Risk in the Setting of Use Causes Hypokalemia and/or
Hypomagnesemia
Reduces
Elimination of a QT/TdP Drug
Use in cLQTS
Bradycardia Hypokalemia/
Hypomagnesemia
Excesive Dose Use with Concomitant QT/TdP Drug Impaired Drug
Elimination
Abiraterone X
Amantadine X X X X
Amisulpride X X X
Amitriptyline X X X X X
Amphotericin B X X
Amsacrine X
Atazanavir X
Bendroflumethiazide X X
Chloral hydrate X
Cimetidine X X X X
Clomipramine X X X
Diphenhydramine X
Doxepin X X X X
Eperisone X
Esomeprazole X X
Famotidine X X X X
Fluoxetine X X X X X
Fluvoxamine X X X X
Furosemide X X
Galantamine X X X X
Garenoxacin X X
Hydrochlorothiazide X
Hydroxyzine X X X X
Indapamide X X
Itraconazole X X
Ivabradine X X X X
Ketoconazole X X X
Lansoprazol X X
Loperamide X X
Metoclopramide X X X X
Metolazone X X X X
Metronidazole X X
Nelfinavir X X X
Olanzapine X X
Omeprazole X X
Pantoprazole X X
Paroxetine X
Piperacilin/tazobactam X X X X
Posaconazole X X X X X
Propafenone X X X
Quetiapine X X X X X
Quinine sulfate X X X
Ranolazine X X X X
Risperidone X X X X
Sertraline X X X X
Solifenacin X X X
Telaprevir X X
Torsemide X X
Trazodone X X X X
Voriconazole X X X
Ziprasidone X X X X

Adapted from: CredibleMeds® list of drugs with a conditional risk for TdP [24].