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Mechanism of action underlying the anti-inflammatory effect induced by OADP in LPS-stimulated RAW264.7 cells, after 72 h of treatment, at the ½ IC50 and ¾ IC50 concentrations. This process triggers the inhibition of phosphorylation of IκBα, the inhibition of the pro-inflammatory cytokines TNF-α and IL-1β. Inhibition of the inflammatory mediators COX-2 and iNOS, induced inhibition of NO production.
